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. 2016 Nov 22;6(11):e012604. doi: 10.1136/bmjopen-2016-012604

Table 2.

ORs (multivariate analysis) for OAP treatment initiation within 7 days of discharge after the index ACS event

OR 95% CI p Value
Age at index (years) vs ≤65
 >65 to ≤75 1.02 0.94 to 1.10 0.693
 >75 to ≤85 0.86 0.79 to 0.95 0.002
 >85 0.57 0.52 to 0.64 <0.001
 Women vs men 0.82 0.79 to 0.87 <0.001
Type of index ACS event vs
unstable angina pectoris
 STEMI 2.63 2.45 to 2.82 <0.001
 NSTEMI 1.66 1.56 to 1.76 <0.001
Invasive procedure vs none
(during the total index event hospitalisation)
 Coronary angiography only 2.09 1.96 to 2.22 <0.001
 PCI 19.51 18.31 to 20.79 <0.001
 CABG 0.28 0.25 to 0.31 <0.001
Comorbidity history yes vs no
 Previous ACS event 1.14 1.03 to 1.27 0.011
 Previous invasive evaluation/treatment 1.02 0.93 to 1.11 0.629
 OAP use at baseline 3.69 3.30 to 4.13 <0.001
 Heart failure 0.78 0.71 to 0.85 <0.001
 Hypertension 0.98 0.91 to 1.05 0.541
 Hyperlipidaemia 1.05 0.99 to 1.12 0.106
 Stroke 0.86 0.78 to 0.95 0.002
 Major bleedings 0.71 0.63 to 0.80 <0.001
 Atrial fibrillation 0.62 0.53 to 0.74 <0.001
 Warfarin use at baseline 0.62 0.55 to 0.69 <0.001
 Diabetes mellitus 0.92 0.84 to 1.01 0.086
 Dementia/Alzheimer's disease 0.51 0.44 to 0.59 <0.001
Charlson Comorbidity Index vs 0
 1 1.12 0.98 to 1.27 0.100
 2 1.02 0.90 to 1.17 0.726
 3 to 5 0.77 0.67 to 0.89 <0.001
 6 to 9 0.62 0.52 to 0.73 <0.001
 ≥10 0.64 0.46 to 0.90 0.010
Cohort entry year vs 2009
 2010 0.84 0.79 to 0.91 <0.001
 2011 1.61 1.50 to 1.72 <0.001
 2012 1.53 1.42 to 1.64 <0.001
 2013 1.67 1.55 to 1.79 <0.001

ACS, acute coronary syndrome; CABG, coronary artery bypass grafting; NSTEMI, non-ST elevation myocardial infarction; OAP, oral antiplatelet; PCI, percutaneous coronary intervention; STEMI, ST elevation myocardial infarction.