Skip to main content
. Author manuscript; available in PMC: 2017 Feb 19.
Published in final edited form as: ACS Chem Biol. 2015 Dec 14;11(2):435–443. doi: 10.1021/acschembio.5b00639

Table 1.

RNA binding activity of TTP/TIS11d chimeras Electrophoretic mobility shift assays (EMSA) with labeled ARE13 were used to determine the RNA binding activity of each chimera. Each chimera was made by fusing ZF1, the linker or ZF2 from either TTP (red) or TIS11d (blue).

TZF Chimera Kd apparent (nM)
graphic file with name nihms-824492-t0007.jpg 9 ± 2
graphic file with name nihms-824492-t0008.jpg 9 ± 1
graphic file with name nihms-824492-t0009.jpg 42 ± 5
graphic file with name nihms-824492-t0010.jpg 15 ± 9
graphic file with name nihms-824492-t0011.jpg 15 ± 3
graphic file with name nihms-824492-t0012.jpg 19 ± 10
graphic file with name nihms-824492-t0013.jpg 15 ± 5
graphic file with name nihms-824492-t0014.jpg 23 ± 6