Table 1.
Demographics of studied patients with age-related cataract and controls
| Parameter | Cataract | Controls | p-value |
|---|---|---|---|
| Age (years) | n = 103 | n = 22 | |
| 71 ± 10.9 | 70 ± 3.4 | 0.35 | |
| Sex | n = 103 | n = 22 | |
| Female | 61 (59.2) | 16 (72.7) | 0.24 |
| Male | 42 (40.8) | 6 (27.3) | |
| Type of lens opacitya | n = 100 | ||
| Nuclear | 93 (93.0) | - | - |
| Cortical | 42 (42.0) | - | |
| Posterior subcapsular | 23 (23.0) | - | |
| Mixed cataract | n = 102 | ||
| Yes | 51 (50.0) | - | - |
| No | 51 (50.0) | - | |
| Diabetes | n = 103 | n = 22 | |
| Yes | 20 (19.4) | - | 0.02 |
| No | 83 (80.6) | 22 (100) | |
| Smoking | n = 103 | n = 22 | |
| Current smoker | 19 (18.4) | 1 (4.5) | 0.11 |
| Ever smokerb | 69 (67.0) | 12 (54.5) | 0.27 |
| Hormonal status | n = 102 | n = 18 | |
| Currently on hormones | 9 (8.8) | 3 (16.7) | 0.31 |
| Ever on hormonesb | 43 (42.2) | 11 (61.1) | 0.14 |
| Menarche / Menopause | |||
| Age at menarche | n = 57 | n = 12 | |
| 13 ± 1.3 | 13 ± 1.4 | 0.64 | |
| Age at menopause | n = 50 | n = 13 | |
| 49 ± 6.8 | 50 ± 3.6 | 0.49 | |
| Years in menopausec | n = 50 | n = 13 | |
| 24 ± 11.7 | 20 ± 5.8 | 0.16 | |
| Reproductive years | n = 48 | n = 12 | |
| 35 ± 6.9 | 38 ± 3.2 | 0.27 | |
Data presented as absolute numbers (%) or mean ± SD. P-values were calculated with Pearson’s chi-square test for categorical parameters and Student’s t-test for continuous parameters
a Both eyes included. Many individuals had more than one subtype, i.e. mixed cataract
b Includes former and current users
c Years in menopause prior to sampling