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. 2016 Nov 29;16:490. doi: 10.1186/s12906-016-1437-x

Table 4.

Antimutagenic effects of 31 methanol plant extracts in S. typhimurium TA98 and TA100 tester strains

Sample #
Conc.(mg/ml)
TA 98 TA 100
5 0.5 0.05 5 0.5 0.05
1 180.00 ± 34.59
[20.68 ± 2.27]
253.67 ± 16.65
[−16.44 ± 1.62]
260.67 ± 15.04
[−19.99 ± 3.68]
662.67 ± 8.09
[39.09 ± 3.14]
877.33 ± 15.18
[14.28 ± 2.58]
1001.33 ± 6.43
[−0.21 ± 0.78]
2 227.10 ± 24.31
[-3.22±2.44]
226.00 ± 11.68
[−2.71 ± 2.23]
233.67 ± 10.01
[−6.27 ± 0.37]
673.67 ± 13.87
[37.79 ± 1.68]
961.67 ± 4.58
[4.54 ± 0.56]
1000.67 ± 20.74
[0.08 ± 1.38]
3 20.4.67±24.09
[8.48±2.39]
199.67 ± 16.86
[11.02 ± 1.06]
190.33 ± 18.15
[15.60 ± 3.47]
657.00 ± 11.36
[39.67 ± 1.38]
760.67 ± 12.67
[29.40 ± 1.54]
940.67 ± 12.50
[6.73 ± 1.54]
4 343.00±32.69
[-62.26±13.47]
200.67 ± 36.35
[10.52 ± 1.49]
227.67 ± 35.81
[−3.22 ± 1.47]
948.67 ± 29.40
[4.66 ± 4.82]
802.00 ± 24.64
[18.01 ± 2.40]
690.00 ± 16.09
32.43 ± 1.57]
5 417.67±14.19
[-97.89±5.84]
347.67 ± 36.07
[−64.30 ± 14.86]
243.00 ± 5.57
[−11.36 ± 2.29]
955.00 ± 10.15
[9.89 ± 0.99]
760.00 ± 26.63
[38.88 ± 2.60]
803.55 ± 34.075
[24.99 ± 3.32]
6 190.67±24.09
[15.61 ± 9.92]
177.67 ± 17.78
[22.23 ± 7.32]
159.33 ± 30.83
[31.39 ± 12.70]
518.00 ± 26.51
[52.19 ± 4.53]
613.67 ± 17.52
[45.50 ± 1.71]
635.33 ± 12.66
[42.39 ± 1.23]
Solvent blank 24.2 ± 5.63 134.40 ± 3.53
Positive control 220.67 ± 10.97 1001.00 ± 17.43
7 230.67 ± 21.50
[−11.33 ± 1.08]
110.00 ± 7.94
[53.39 ± 4.00]
182.67 ± 8.33
[14.56 ± 4.20]
995.00 ± 29.87
[15.52 ± 2.35]
903.00 ± 14.53
[24.35 ± 11.42]
1116.67 ± 8.54
[3.79 ± 6.72]
8 285.33 ± 29.50
[−40.99 ± 1.49]
156.33 ± 16.44
[28.59 ± 2.84]
157.67 ± 9.45
[28.05 ± 4.78]
843.33 ± 9.45
[30.14 ± 7.43]
733.33 ± 12.67
[40.74 ± 9.95]
826.67 ± 10.02
[31.75 ± 7.87]
9 170.67 ± 10.69
[2.03 ± 5.39]
164.67 ± 22.68
[24.27 ± 11.40]
176.33 ± 31.66
[17.80 ± 5.79]
853.33 ± 4.04
[29.17 ± 3.18]
1023.00 ± 11.36
[12.82 ± 8.93]
1262.67 ± 10.50
[−10.28 ± 8.26]
10 347.67 ± 20.21
[−74.43 ± 1.76]
232.67 ± 16.26
[−12.40 ± 1.17]
219.67 ± 10.50
[5.39 ± 7.57]
1686.67 ± 9.74
[−51.15 ± 17.75]
1330.00 ± 18.77
[−16.77 ± 6.70]
1253.33 ± 15.14
[−9.38 ± 5.40]
11 252.67 ± 8.14
[−23.19 ± 5.87]
247.67 ± 23.75
[−20.49 ± 1.71]
210.00 ± 14.80
[−0.92 ± 1.07]
1110.00 ± 21.00
[4.43 ± 7.49]
1243.33 ± 4.04
[−8342 ± 1.44]
1377.33 ± 13.11
[−21.33 ± 4.68]
12 180.00 ± 8.88
[15.64 ± 6.41]
230.00 ± 18.52
[−27.51 ± 13.35]
223.67 ± 26.10
[−7.55 ± 1.88]
681.40 ± 15.03
[45.75 ± 11.43]
873.33 ± 3.05
[27.25 ± 1.09]
1006.67 ± 10.21
[14.39 ± 3.64]
Solvent blank 23.60 ± 2.06 118.06 ± 3.21
Positive control 209.00 ± 2.00 1156.80 ± 17.43
13 209.00 ± 19.00
[7.68 ± 1.73]
273.00 ± 24.06
[−23.71 ± 2.17]
234.67 ± 13.27
[−4.58 ± 1.21]
976.00 ± 13.05
[26.66 ± 3.97]
1108.33 ± 2.00
[15.54 ± 0.61]
1243.67 ± 27.30
[4.17 ± 8.31]
14 333.00 ± 10.44
[−53.14 ± 9.51]
207.00 ± 13.00
[8.67 ± 1.81]
156.00 ± 15.17
[33.68 ± 3.21]
1242.00 ± 7.94
[4.31 ± 2.42]
1216.67 ± 2.11
[6.44 ± 6.73]
1250.00 ± 16.77
[3.64 ± 5.11]
15 238.67 ± 1.15
[−6.54 ± 2.47]
219.33 ± 5.50
[2.39 ± 1.02]
252.00 ± 17.69
[−13.40 ± 1.61]
1220.00 ± 10.26
[6.16 ± 3.13]
1236.00 ± 8.00
[4.82 ± 2.44]
1313.33 ± 26.51
[−1.68 ± 2.07]
16 175.33 ± 8.73
[24.36 ± 4.71]
187.67 ± 29.14
18.48 ± 5.72]
163.33 ± 9.29
[30.25 ± 5.01]
719.67 ± 5.04
[48.19 ± 8.21]
976.33 ± 13.57
[26.63 ± 3.18]
1209.67 ± 10.44
[7.03 ± 2.45]
17 179.00 ± 5.20
[22.40 ± 2.80]
177.00 ± 17.35
[23.38 ± 9.36]
216.33 ± 8.08
[4.25 ± 2.36]
576.00 ± 14.01
[60.26 ± 3.28]
723.33 ± 5.29
[47.88 ± 0.35]
836.67 ± 3.21
[38.36 ± 0.75]
18 220.00 ± 2.00
[2.29 ± 1.08]
224.00 ± 7.00
[0.33 ± 3.78]
210.67 ± 6.81
[7.19 ± 3.67]
700.00 ± 14.73
[49.84 ± 3.45]
886.67 ± 9.59
[34.16 ± 6.94]
880.00 ± 13.43
[34.72 ± 3.14]
Solvent blank 20.8 ± 4.18 103.00 ± 3.74
Positive control 224.67 ± 9.45 1293.33 ± 8.08
19 322.33 ± 49.52
[−51.77 ± 2.48]
195.50 ± 16.65
[12.33 ± 8.35]
182.67 ± 5.13
[19.06 ± 2.57]
1350.00 ± 30.00
[−35.35 ± 2.24]
1450.33 ± 10.27
[−46.23 ± 17.88]
1570.0 ± 26.46
[−59.28 ± 7.01]
20 144.33 ± 5.69
[38.28 ± 2.28]
159.00 ± 13.53
[30.69 ± 6.78]
226.00 ± 15.13
[−3.20 ± 7.59]
1056.67 ± 15.27
[−3.44 ± 1.68]
1653.33 ± 35.12
[−68.35 ± 7.02]
1396.67 ± 20.82
[−40.43 ± 4.32]
21 123.33 ± 16.04
[48.65 ± 8.04]
171.67 ± 10.02
[24.62 ± 5.02]
164.67 ± 15.01
[28.16 ± 7.52]
903.33 ± 5.77
[13.23 ± 4.51]
1112.67 ± 11.01
[−9.53 ± 10.40]
600.00 ± 34.64
[46.23 ± 3.016]
22 130.67 ± 26.01
[45.36 ± 15.46]
180.00 ± 4.00
[20.07 ± 2.37]
205.00 ± 10.44
[7.42 ± 6.21]
590.00 ± 5.77
[24.84 ± 0.59]
880.00 ± 26.46
[15.77 ± 4.03]
943.33 ± 11.55
[8.88 ± 5.62]
23 209.67 ± 4.51
[5.40 ± 2.68]
172.33 ± 10.69
[24.12 ± 6.36]
190.00 ± 8.72
[15.01 ± 5.18]
1017.67 ± 5.01
[0.80 ± 1.95]
1005.67 ± 10.69
[2.10 ± 4.91]
710.00 ± 10.16
[25.56 ± 5.60]
24 144.33 ± 21.13
[38.28 ± 12.56]
183.33 ± 16.17
[18.30 ± 9.61]
173.67 ± 13.65
[23.61 ± 8.12]
816.67 ± 22.66
[22.66 ± 2.12]
1011.33 ± 12.05
[1.49 ± 3.86]
870.00 ± 26.46
[16.86 ± 9..48]
Solvent blank 22.00 ± 4.61 105.67 ± 5.59
Positive control 219.67 ± 9.89 1025.60 ± 35.79
25 1607.67 ± 4.93
[27.89 ± 3.20]
174.67 ± 13.32
[20.24 ± 8.69]
186.33 ± 8.02
[13.68 ± 5.21]
856.67 ± 15.27
[22.76 ± 7.68]
1040.00 ± 10.00
[3.76 ± 6.13]
1180.00 ± 20.00
[−10.73 ± 0.63]
26 217.67 ± 14.29
[−3.28 ± 9.28]
186.33 ± 8.96
[13.68 ± 8.82]
190.00 ± 14.00
[11.49 ± 9.09]
870.00 ± 20.00
[21.38 ± 1.25]
1126.67 ± 30.55
[−5.22 ± 6.45]
1132.00 ± 25.53
[−5.77 ± 3.90]
27 194.67 ± 6.66
[9.30 ± 5.44]
202.33 ± 8.39
[4.92 ± 4.87]
175.33 ± 7.50
[19.69 ± 8.34]
1203.33 ± 26.17
[−13.16 ± 2.66]
1035.00 ± 5.00
[4.28 ± 3.74]
1057.33 ± 11.59
[1.97 ± 1.42]
28 223.33 ± 17.01
[−6.56 ± 1.13]
168.33 ± 14.84
[23.52 ± 9.89]
141.33 ± 13.58
[25.16 ± 9.09]
911.00 ± 20.05
[17.13 ± 2.75]
749.67 ± 11.93
[33.85 ± 9.43]
580.00 ± 17.32
[51.44 ± 7.54]
29 261.67 ± 13.05
[−54.16 ± 8.70]
165.67 ± 5.13
[−2.19 ± 3.42]
155.00 ± 19.97
[16.95 ± 3.32]
1031.67 ± 10.41
[4.63 ± 4.31]
760.00 ± 20.00
[32.78 ± 6.84]
746.67 ± 15.27
[34.16 ± 2.87]
30 200.00 ± 13.23
[6.01 ± 8.82]
179.50 ± 14.19
[17.23 ± 9.46]
190.67 ± 17.47
[11.49 ± 1.64]
583.33 ± 20.82
[51.09 ± 7.23]
476.67 ± 15.27
[62.14 ± 0.66]
615.00 ± 35.00
[47.81 ± 1.16]
31 71.00 ± 7.00
[76.58 ± 4.67]
201.67 ± 9.45
[5.47 ± 6.30]
171.33 ± 19.65
[21.88 ± 13.1]
118.00 ± 15.62
[99.32 ± 2.95]
160.00 ± 10.00
[94.96 ± 7.25]
746.67 ± 45.09
[34.16 ± 5.59]
Solvent blank 28.2 ± 6.57 111.40 ± 11.13
Positive control 211.67 ± 7.57 1076.33 ± 26.95

The results are expressed as mean number of revertants/plate (± SD) percentage antimutagenicity [in squared brackets]