Table 4.
Sample # Conc.(mg/ml) |
TA 98 | TA 100 | ||||
---|---|---|---|---|---|---|
5 | 0.5 | 0.05 | 5 | 0.5 | 0.05 | |
1 | 180.00 ± 34.59 [20.68 ± 2.27] |
253.67 ± 16.65 [−16.44 ± 1.62] |
260.67 ± 15.04 [−19.99 ± 3.68] |
662.67 ± 8.09 [39.09 ± 3.14] |
877.33 ± 15.18 [14.28 ± 2.58] |
1001.33 ± 6.43 [−0.21 ± 0.78] |
2 | 227.10 ± 24.31 [-3.22±2.44] |
226.00 ± 11.68 [−2.71 ± 2.23] |
233.67 ± 10.01 [−6.27 ± 0.37] |
673.67 ± 13.87 [37.79 ± 1.68] |
961.67 ± 4.58 [4.54 ± 0.56] |
1000.67 ± 20.74 [0.08 ± 1.38] |
3 | 20.4.67±24.09 [8.48±2.39] |
199.67 ± 16.86 [11.02 ± 1.06] |
190.33 ± 18.15 [15.60 ± 3.47] |
657.00 ± 11.36 [39.67 ± 1.38] |
760.67 ± 12.67 [29.40 ± 1.54] |
940.67 ± 12.50 [6.73 ± 1.54] |
4 | 343.00±32.69 [-62.26±13.47] |
200.67 ± 36.35 [10.52 ± 1.49] |
227.67 ± 35.81 [−3.22 ± 1.47] |
948.67 ± 29.40 [4.66 ± 4.82] |
802.00 ± 24.64 [18.01 ± 2.40] |
690.00 ± 16.09 32.43 ± 1.57] |
5 | 417.67±14.19 [-97.89±5.84] |
347.67 ± 36.07 [−64.30 ± 14.86] |
243.00 ± 5.57 [−11.36 ± 2.29] |
955.00 ± 10.15 [9.89 ± 0.99] |
760.00 ± 26.63 [38.88 ± 2.60] |
803.55 ± 34.075 [24.99 ± 3.32] |
6 | 190.67±24.09 [15.61 ± 9.92] |
177.67 ± 17.78 [22.23 ± 7.32] |
159.33 ± 30.83 [31.39 ± 12.70] |
518.00 ± 26.51 [52.19 ± 4.53] |
613.67 ± 17.52 [45.50 ± 1.71] |
635.33 ± 12.66 [42.39 ± 1.23] |
Solvent blank | 24.2 ± 5.63 | 134.40 ± 3.53 | ||||
Positive control | 220.67 ± 10.97 | 1001.00 ± 17.43 | ||||
7 | 230.67 ± 21.50 [−11.33 ± 1.08] |
110.00 ± 7.94 [53.39 ± 4.00] |
182.67 ± 8.33 [14.56 ± 4.20] |
995.00 ± 29.87 [15.52 ± 2.35] |
903.00 ± 14.53 [24.35 ± 11.42] |
1116.67 ± 8.54 [3.79 ± 6.72] |
8 | 285.33 ± 29.50 [−40.99 ± 1.49] |
156.33 ± 16.44 [28.59 ± 2.84] |
157.67 ± 9.45 [28.05 ± 4.78] |
843.33 ± 9.45 [30.14 ± 7.43] |
733.33 ± 12.67 [40.74 ± 9.95] |
826.67 ± 10.02 [31.75 ± 7.87] |
9 | 170.67 ± 10.69 [2.03 ± 5.39] |
164.67 ± 22.68 [24.27 ± 11.40] |
176.33 ± 31.66 [17.80 ± 5.79] |
853.33 ± 4.04 [29.17 ± 3.18] |
1023.00 ± 11.36 [12.82 ± 8.93] |
1262.67 ± 10.50 [−10.28 ± 8.26] |
10 | 347.67 ± 20.21 [−74.43 ± 1.76] |
232.67 ± 16.26 [−12.40 ± 1.17] |
219.67 ± 10.50 [5.39 ± 7.57] |
1686.67 ± 9.74 [−51.15 ± 17.75] |
1330.00 ± 18.77 [−16.77 ± 6.70] |
1253.33 ± 15.14 [−9.38 ± 5.40] |
11 | 252.67 ± 8.14 [−23.19 ± 5.87] |
247.67 ± 23.75 [−20.49 ± 1.71] |
210.00 ± 14.80 [−0.92 ± 1.07] |
1110.00 ± 21.00 [4.43 ± 7.49] |
1243.33 ± 4.04 [−8342 ± 1.44] |
1377.33 ± 13.11 [−21.33 ± 4.68] |
12 | 180.00 ± 8.88 [15.64 ± 6.41] |
230.00 ± 18.52 [−27.51 ± 13.35] |
223.67 ± 26.10 [−7.55 ± 1.88] |
681.40 ± 15.03 [45.75 ± 11.43] |
873.33 ± 3.05 [27.25 ± 1.09] |
1006.67 ± 10.21 [14.39 ± 3.64] |
Solvent blank | 23.60 ± 2.06 | 118.06 ± 3.21 | ||||
Positive control | 209.00 ± 2.00 | 1156.80 ± 17.43 | ||||
13 | 209.00 ± 19.00 [7.68 ± 1.73] |
273.00 ± 24.06 [−23.71 ± 2.17] |
234.67 ± 13.27 [−4.58 ± 1.21] |
976.00 ± 13.05 [26.66 ± 3.97] |
1108.33 ± 2.00 [15.54 ± 0.61] |
1243.67 ± 27.30 [4.17 ± 8.31] |
14 | 333.00 ± 10.44 [−53.14 ± 9.51] |
207.00 ± 13.00 [8.67 ± 1.81] |
156.00 ± 15.17 [33.68 ± 3.21] |
1242.00 ± 7.94 [4.31 ± 2.42] |
1216.67 ± 2.11 [6.44 ± 6.73] |
1250.00 ± 16.77 [3.64 ± 5.11] |
15 | 238.67 ± 1.15 [−6.54 ± 2.47] |
219.33 ± 5.50 [2.39 ± 1.02] |
252.00 ± 17.69 [−13.40 ± 1.61] |
1220.00 ± 10.26 [6.16 ± 3.13] |
1236.00 ± 8.00 [4.82 ± 2.44] |
1313.33 ± 26.51 [−1.68 ± 2.07] |
16 | 175.33 ± 8.73 [24.36 ± 4.71] |
187.67 ± 29.14 18.48 ± 5.72] |
163.33 ± 9.29 [30.25 ± 5.01] |
719.67 ± 5.04 [48.19 ± 8.21] |
976.33 ± 13.57 [26.63 ± 3.18] |
1209.67 ± 10.44 [7.03 ± 2.45] |
17 | 179.00 ± 5.20 [22.40 ± 2.80] |
177.00 ± 17.35 [23.38 ± 9.36] |
216.33 ± 8.08 [4.25 ± 2.36] |
576.00 ± 14.01 [60.26 ± 3.28] |
723.33 ± 5.29 [47.88 ± 0.35] |
836.67 ± 3.21 [38.36 ± 0.75] |
18 | 220.00 ± 2.00 [2.29 ± 1.08] |
224.00 ± 7.00 [0.33 ± 3.78] |
210.67 ± 6.81 [7.19 ± 3.67] |
700.00 ± 14.73 [49.84 ± 3.45] |
886.67 ± 9.59 [34.16 ± 6.94] |
880.00 ± 13.43 [34.72 ± 3.14] |
Solvent blank | 20.8 ± 4.18 | 103.00 ± 3.74 | ||||
Positive control | 224.67 ± 9.45 | 1293.33 ± 8.08 | ||||
19 | 322.33 ± 49.52 [−51.77 ± 2.48] |
195.50 ± 16.65 [12.33 ± 8.35] |
182.67 ± 5.13 [19.06 ± 2.57] |
1350.00 ± 30.00 [−35.35 ± 2.24] |
1450.33 ± 10.27 [−46.23 ± 17.88] |
1570.0 ± 26.46 [−59.28 ± 7.01] |
20 | 144.33 ± 5.69 [38.28 ± 2.28] |
159.00 ± 13.53 [30.69 ± 6.78] |
226.00 ± 15.13 [−3.20 ± 7.59] |
1056.67 ± 15.27 [−3.44 ± 1.68] |
1653.33 ± 35.12 [−68.35 ± 7.02] |
1396.67 ± 20.82 [−40.43 ± 4.32] |
21 | 123.33 ± 16.04 [48.65 ± 8.04] |
171.67 ± 10.02 [24.62 ± 5.02] |
164.67 ± 15.01 [28.16 ± 7.52] |
903.33 ± 5.77 [13.23 ± 4.51] |
1112.67 ± 11.01 [−9.53 ± 10.40] |
600.00 ± 34.64 [46.23 ± 3.016] |
22 | 130.67 ± 26.01 [45.36 ± 15.46] |
180.00 ± 4.00 [20.07 ± 2.37] |
205.00 ± 10.44 [7.42 ± 6.21] |
590.00 ± 5.77 [24.84 ± 0.59] |
880.00 ± 26.46 [15.77 ± 4.03] |
943.33 ± 11.55 [8.88 ± 5.62] |
23 | 209.67 ± 4.51 [5.40 ± 2.68] |
172.33 ± 10.69 [24.12 ± 6.36] |
190.00 ± 8.72 [15.01 ± 5.18] |
1017.67 ± 5.01 [0.80 ± 1.95] |
1005.67 ± 10.69 [2.10 ± 4.91] |
710.00 ± 10.16 [25.56 ± 5.60] |
24 | 144.33 ± 21.13 [38.28 ± 12.56] |
183.33 ± 16.17 [18.30 ± 9.61] |
173.67 ± 13.65 [23.61 ± 8.12] |
816.67 ± 22.66 [22.66 ± 2.12] |
1011.33 ± 12.05 [1.49 ± 3.86] |
870.00 ± 26.46 [16.86 ± 9..48] |
Solvent blank | 22.00 ± 4.61 | 105.67 ± 5.59 | ||||
Positive control | 219.67 ± 9.89 | 1025.60 ± 35.79 | ||||
25 | 1607.67 ± 4.93 [27.89 ± 3.20] |
174.67 ± 13.32 [20.24 ± 8.69] |
186.33 ± 8.02 [13.68 ± 5.21] |
856.67 ± 15.27 [22.76 ± 7.68] |
1040.00 ± 10.00 [3.76 ± 6.13] |
1180.00 ± 20.00 [−10.73 ± 0.63] |
26 | 217.67 ± 14.29 [−3.28 ± 9.28] |
186.33 ± 8.96 [13.68 ± 8.82] |
190.00 ± 14.00 [11.49 ± 9.09] |
870.00 ± 20.00 [21.38 ± 1.25] |
1126.67 ± 30.55 [−5.22 ± 6.45] |
1132.00 ± 25.53 [−5.77 ± 3.90] |
27 | 194.67 ± 6.66 [9.30 ± 5.44] |
202.33 ± 8.39 [4.92 ± 4.87] |
175.33 ± 7.50 [19.69 ± 8.34] |
1203.33 ± 26.17 [−13.16 ± 2.66] |
1035.00 ± 5.00 [4.28 ± 3.74] |
1057.33 ± 11.59 [1.97 ± 1.42] |
28 | 223.33 ± 17.01 [−6.56 ± 1.13] |
168.33 ± 14.84 [23.52 ± 9.89] |
141.33 ± 13.58 [25.16 ± 9.09] |
911.00 ± 20.05 [17.13 ± 2.75] |
749.67 ± 11.93 [33.85 ± 9.43] |
580.00 ± 17.32 [51.44 ± 7.54] |
29 | 261.67 ± 13.05 [−54.16 ± 8.70] |
165.67 ± 5.13 [−2.19 ± 3.42] |
155.00 ± 19.97 [16.95 ± 3.32] |
1031.67 ± 10.41 [4.63 ± 4.31] |
760.00 ± 20.00 [32.78 ± 6.84] |
746.67 ± 15.27 [34.16 ± 2.87] |
30 | 200.00 ± 13.23 [6.01 ± 8.82] |
179.50 ± 14.19 [17.23 ± 9.46] |
190.67 ± 17.47 [11.49 ± 1.64] |
583.33 ± 20.82 [51.09 ± 7.23] |
476.67 ± 15.27 [62.14 ± 0.66] |
615.00 ± 35.00 [47.81 ± 1.16] |
31 | 71.00 ± 7.00 [76.58 ± 4.67] |
201.67 ± 9.45 [5.47 ± 6.30] |
171.33 ± 19.65 [21.88 ± 13.1] |
118.00 ± 15.62 [99.32 ± 2.95] |
160.00 ± 10.00 [94.96 ± 7.25] |
746.67 ± 45.09 [34.16 ± 5.59] |
Solvent blank | 28.2 ± 6.57 | 111.40 ± 11.13 | ||||
Positive control | 211.67 ± 7.57 | 1076.33 ± 26.95 |
The results are expressed as mean number of revertants/plate (± SD) percentage antimutagenicity [in squared brackets]