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. 2016 Nov 30;14:331. doi: 10.1186/s12967-016-1086-3

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Renal structure in IUGR-BET offspring more affected than in IUGR-LPD offspring. Nephron number (A), glomerular sclerosis (B), and mean glomerular volume (MGV; C) in 22-month-old normal birth weight (NBW, open bars), maternal low-protein diet (LPD, grey bars), and BET (BET, black bars) offspring, according to gender (n = 8–12/group). Glomerular sclerosis is expressed as the mean ratio of Sirius red-stained areas to total glomerular capillary areas. Value are mean ± SEM; (n = 8–10). Significance differences (p < 0.05) among groups are indicated by different letters (e.g., a is different from b and c)