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. 2016 Nov 17;13(11):1149. doi: 10.3390/ijerph13111149

Table 4.

Organ weights of rats following injection of GO in the seven-day subchronic toxicity study.

Organ Weights Sham GO 2.5 mg/kg GO 5 mg/kg GO 10 mg/kg
Brain
Absolute organ weight (g) 1.68 ± 0.04 1.72 ± 0.05 1.75 ± 0.06 1.68 ± 0.06
organ coefficient % 1.30 ± 0.12 1.32 ± 0.12 1.34 ± 0.12 1.29 ± 0.16
Heart
Absolute organ weight (g) 0.55 ± 0.05 0.48 ± 0.05 0.52 ± 0.04 0.5 ± 0.07
organ coefficient % 0.43 ± 0.05 0.36 ± 0.05 0.37 ± 0.03 0.38 ± 0.03
Liver
Absolute organ weight (g) 4.36 ± 0.14 4.37 ± 0.18 4.04 ± 0.37 3.83 ± 0.42
organ coefficient % 3.33 ± 0.36 3.34 ± 0.39 3.03 ± 0.3 2.99 ± 0.09
Spleen
Absolute organ weight (g) 0.38 ± 0.06 0.39 ± 0.05 0.44 ± 0.03 0.4 ± 0.04
organ coefficient % 0.31 ± 0.06 0.28 ± 0.03 0.30 ± 0.03 0.31 ± 0.06
Lung
Absolute organ weight (g) 0.84 ± 0.12 0.79 ± 0.04 0.82 ± 0.16 0.95 ± 0.18
organ coefficient % 0.67 ± 0.08 0.58 ± 0.07 0.67 ± 0.06 0.71 ± 0.06
Kidney
Absolute organ weight (g) 0.03 ± 0.009 0.04 ± 0.005 0.03 ± 0.005 0.031 ± 0.005
organ coefficient % 0.86 ± 0.08 0.85 ± 0.09 0.82 ± 0.04 0.80 ± 0.03
Thymus gland
Absolute organ weight (g) 0.26 ± 0.07 0.33 ± 0.043 0.32 ± 0.014 0.33 ± 0.038
organ coefficient % 0.22 ± 0.05 0.27 ± 0.05 0.25 ± 0.02 0.25 ± 0.03
Adrenal gland (×100)
Absolute organ weight (g) 3.23 ± 0.9 4.22 ± 0.52 3.08 ± 0.48 3.1 ± 0.47
organ coefficient % 2.08 ± 0.45 2.49 ± 0.44 2.17 ± 0.41 2.17 ± 0.25
Prostate gland
Absolute organ weight (g) 0.87 ± 0.04 0.81 ± 0.04 0.92 ± 0.16 0.95 ± 0.15
organ coefficient % 0.08 ± 0.04 0.07 ± 0.02 0.07 ± 0.02 0.05 ± 0.02
Testis
Absolute organ weight (g) 1.05 ± 0.26 1.19 ± 0.18 1.14 ± 0.19 1.11 ± 0.06
organ coefficient % 0.86 ± 0.23 0.85 ± 0.09 0.88 ± 0.17 0.94 ± 0.14
Epididymis
Absolute organ weight (g) 0.7 ± 0.077 0.77 ± 0.19 0.82 ± 0.17 0.79 ± 0.06
organ coefficient % 0.57 ± 0.11 0.65 ± 0.15 0.64 ± 0.08 0.61 ± 0.03