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Mean expression scores of wtERa, ERa36 and ER-beta in primary HCC compared to secondary HCC. (a) Decreased wtERa (P < 0.010) and increased ERa36 (P < 0.008) in tumor tissues in Cohort P; and (b) Decreased ERa36 (P < 0.001) in tumor tissues in Cohort S. P-values were calculated using the paired sample t test. wtERa, blue; ERa36, green; ERb, brown; T, tumor tissue; N, adjacent non-tumor tissue; error bars, 95 % confident interval
