Table 3.
The MBC of EF60 against standard strains and clinical isolates
| Strain and compound | MIC (μg/mL) | MBC (μg/mL) | MBC/MIC |
|---|---|---|---|
| S. aureus ATCC 25923 | |||
| EF60 | 32 | >256 | >8 |
| Berberine | 128 | >512 | >4 |
| Vancomycin | 2 | 2 | 1 |
| S. aureus ATCC 29213 | |||
| EF60 | 16 | 32 | 2 |
| Berberine | 64 | >512 | >8 |
| Vancomycin | 1 | 2 | 2 |
| S. aureus ATCC 43300 | |||
| EF60 | 8 | >128 | >8 |
| Berberine | 128 | 128 | 1 |
| Vancomycin | 2 | 2 | 1 |
| S. aureus 3211 | |||
| EF60 | 8 | >128 | >16 |
| Berberine | 128 | 256 | 2 |
| Vancomycin | 1 | 2 | 2 |
| S. aureus 3304 | |||
| EF60 | 16 | 32 | 2 |
| Berberine | 128 | 128 | 1 |
| Vancomycin | 1 | 1 | 1 |
MIC minimum inhibitory concentration
MBC minimum bactericidal concentration