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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Qual Life Res. 2015 Oct 17;25(3):547–557. doi: 10.1007/s11136-015-1156-7

Table 2.

Ten most common symptom pairs for social media and research study groups based on number of co-occurrences (social media n = 50,426; research study n = 653)

Social media group Research study group T1 moderate and
severe symptoms
Research study group T2 severe symptoms only



Symptom pair Co-occurrence
(%)
Symptom pair Co-occurrence
(%)
Symptom pair Co-occurrence
(%)
General aches–
 headaches
141 (0.28) Fatigue–restless sleep 242 (37.1) Hot flashes–night sweats 36 (5.5)
Fatigue–general aches 89 (0.18) Hot flashes–night
 sweats
146 (22.4) Fatigue–muscle pains 30 (4.6)
Fatigue–nausea 64 (0.13) Fatigue–muscle pains 140 (21.4) Fatigue–restless sleep 29 (4.4)
Depressed–fatigue 59 (0.12) Hot flashes–restless
 sleep
126 (19.3) Joint pains–muscle pains 29 (4.4)
General aches–nausea 49 (0.10) Muscle pains–restless
 sleep
125 (19.1) General aches–muscle pains 27 (4.1)
Hot flashes–mood
 changes
42 (0.08) Decreased efficiency–
 fatigue
123 (18.8) Fatigue–lowered work performance 26 (4.0)
Depressed–general
 aches
39 (0.08) Fatigue–night sweats 121 (18.5) Hot flashes–restless sleep 23 (3.5)
Fatigue–hot flashes 31 (0.06) Night sweats–restless
 sleep
120 (18.4) Decreased efficiency–fatiguea 22 (3.4)
General aches–muscle
 pains
31 (0.06) Depressed–fatigue 118 (18.1) Fatigue–nausea 22 (3.4)
Fatigue–headaches 29 (0.06) Fatigue–hot flashes 117 (17.9) General aches–joint pains 22 (3.4)
Loss of interest in work–lowered work
 performance
22 (3.4)
a

Four-way tie for eighth place