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. 2016 Nov 29;13:198. doi: 10.1186/s12985-016-0661-9

Table 2.

The pooled positive rates of clinical charactersa

Pooled 95% CI Simple pooled
I2 (%) p Rate Low Up Rate
Feverb 85.20 <0.05 0.99 0.97 1.00 0.94
Leucopeniac 0.00 0.70 0.88 0.82 0.94 0.73
Thrombocytopeniad 71.00 0.03 0.83 0.51 1.16 0.65
Anorexia 58.70 0.09 0.83 0.76 0.91 0.85
Weakness 46.70 0.09 0.74 0.54 0.94 0.83
Nausea 34.60 0.21 0.54 0.49 0.60 0.55
Myalgias 49.60 0.09 0.51 0.42 0.60 0.62
Proteinuria 62.30 0.10 0.50 0.39 0.61 0.51
Lymphadenopathy 61.80 0.05 0.39 0.29 0.49 0.35
Vomiting 55.50 0.05 0.39 0.33 0.46 0.38
Joint pain 0.00 0.33 0.35 0.27 0.43 0.28
Chills 30.10 0.24 0.32 0.22 0.43 0.27
Diarrhea 66.60 0.02 0.31 0.23 0.39 0.34
Hematuria 25.10 0.25 0.29 0.22 0.36 0.29
Cough 67.60 0.08 0.28 0.20 0.36 0.26
Abdominal pain 26.80 0.25 0.22 0.15 0.29 0.29
Dizziness 0.00 0.53 0.20 0.16 0.24 0.25
Headache 19.80 0.29 0.17 0.13 0.21 0.22
Case fatality rate 10.60 0.35 0.16 0.13 0.19 0.16
Petechiae 16.70 0.31 0.08 0.06 0.11 0.11

aThe data would be excluded if it did not mention the corresponding clinical character

bFever was defined as body temperature ≥38 °C in references [1, 5, 32, 33]; ≥37.5 °C in references [8, 9]; ≥39 °C in reference [6]

cLeucopenia was defined as leukocyte count <4.0 × 109/L

dThrombocytopenia was defined as platelet count <150 × 109/L in references [5, 32, 33]; <100 × 109/L in references [1, 810]