Table 2.
Pooled | 95% CI | Simple pooled | ||||
---|---|---|---|---|---|---|
I2 (%) | p | Rate | Low | Up | Rate | |
Feverb | 85.20 | <0.05 | 0.99 | 0.97 | 1.00 | 0.94 |
Leucopeniac | 0.00 | 0.70 | 0.88 | 0.82 | 0.94 | 0.73 |
Thrombocytopeniad | 71.00 | 0.03 | 0.83 | 0.51 | 1.16 | 0.65 |
Anorexia | 58.70 | 0.09 | 0.83 | 0.76 | 0.91 | 0.85 |
Weakness | 46.70 | 0.09 | 0.74 | 0.54 | 0.94 | 0.83 |
Nausea | 34.60 | 0.21 | 0.54 | 0.49 | 0.60 | 0.55 |
Myalgias | 49.60 | 0.09 | 0.51 | 0.42 | 0.60 | 0.62 |
Proteinuria | 62.30 | 0.10 | 0.50 | 0.39 | 0.61 | 0.51 |
Lymphadenopathy | 61.80 | 0.05 | 0.39 | 0.29 | 0.49 | 0.35 |
Vomiting | 55.50 | 0.05 | 0.39 | 0.33 | 0.46 | 0.38 |
Joint pain | 0.00 | 0.33 | 0.35 | 0.27 | 0.43 | 0.28 |
Chills | 30.10 | 0.24 | 0.32 | 0.22 | 0.43 | 0.27 |
Diarrhea | 66.60 | 0.02 | 0.31 | 0.23 | 0.39 | 0.34 |
Hematuria | 25.10 | 0.25 | 0.29 | 0.22 | 0.36 | 0.29 |
Cough | 67.60 | 0.08 | 0.28 | 0.20 | 0.36 | 0.26 |
Abdominal pain | 26.80 | 0.25 | 0.22 | 0.15 | 0.29 | 0.29 |
Dizziness | 0.00 | 0.53 | 0.20 | 0.16 | 0.24 | 0.25 |
Headache | 19.80 | 0.29 | 0.17 | 0.13 | 0.21 | 0.22 |
Case fatality rate | 10.60 | 0.35 | 0.16 | 0.13 | 0.19 | 0.16 |
Petechiae | 16.70 | 0.31 | 0.08 | 0.06 | 0.11 | 0.11 |
aThe data would be excluded if it did not mention the corresponding clinical character
bFever was defined as body temperature ≥38 °C in references [1, 5, 32, 33]; ≥37.5 °C in references [8, 9]; ≥39 °C in reference [6]
cLeucopenia was defined as leukocyte count <4.0 × 109/L
dThrombocytopenia was defined as platelet count <150 × 109/L in references [5, 32, 33]; <100 × 109/L in references [1, 8–10]