Figure 8.
Model of de novo root organogenesis from leaf explant. De novo regeneration of adventitious root comprises priming, initiation, patterning, and emergence steps. Founder-cell-specific WOX11/12 function as a valve to activate downstream gene expression, such as the WOX5/7 and LBD pathways, which function in root primordium formation. Activation of WOX11/12 and WOX5/7 requires auxin. An unknown factor (X with question mark) might shut down WOX11/12 expression in the root primordium. RC cell, regeneration-competent cell; RF cell, root founder cell; RP, root primordium.