Figure 2.

Comparing growth responses to deficiencies of thiamin, B₆, or folate in rats versus plants. The decline from vitamin sufficiency to deficiency is approximated by a color gradient. For rats, deficiencies were obtained by varying dietary vitamin content; liver was used to assess vitamin status. For plants, the experiments involved vitamin deficient mutants (blk-1 for thiamin in maize; pdx1.3 for B₆ in Arabidopsis) or cell cultures treated with an antifolate drug for folate in Arabidopsis. Whole plants, leaves, or cells were used to assess vitamin status. Data sources: rat thiamin (Rains et al., 1997), rat B₆ (Mackey et al., 2003; Scheer et al., 2005), rat folate (Clifford et al., 1993), maize thiamin (Woodward et al., 2010), Arabidopsis B₆ (Rueschhoff et al., 2013), and Arabidopsis folate (Loizeau et al., 2008).