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. 2016 Dec;148(6):489–501. doi: 10.1085/jgp.201611684

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© 2016 Jin et al.

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Figure 6. — Influence of pulsatile pressure in the para-arterial space on solute movement in brain ECS. (A, left) Schematic showing hydrostatic pressure driven in the para-arterial space water transport across the astrocyte endfoot barrier; (right) para-arterial pressure waveform of amplitude P_amp and frequency 1 Hz. (B) Pseudocolored images showing tracer solute accumulation in the ECS, as in Fig 3, for different P_amp. Parameters: P_f = 0.04 cm/s, D = 10⁻¹⁰ m²/s, and α = 0.2. (C) Kinetics of tracer solute accumulation in ECS for the indicated P_amp.