Fig. 11.

Altered phagocytic activity of RPE cells. The RPE cells in different glucose conditions were incubated with medium containing pHrodo TM green Escherichia coli BioParticles conjugates for different times (5 and 24 h). The cellular fluorescence intensities were determined by FACS analysis. Please note the decreased phagocytic activity of RPE cells in high glucose and osmotic stress conditions compared with normal glucose. The mean fluorescence intensities are shown for each sample. These experiments were repeated with two different isolations of RPE cells with similar results.