Table 2. Survival analysis of 86 852 breast cancer cases in England 2012–2013 with follow-up to 2014.
|
Model 1 |
Model 2 |
Model 3a |
Model 3b |
Model 3c |
Model 3d |
Model 4 |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Adjustments |
Age |
Age
SES Region Como |
Age
SES Region Como
Stage |
Age
SES Region Como
Grade |
Age
SES Region Como
Receptors |
Age
SES Region Como
Morphology |
All covariates |
|||||||||
| Ethnicity | Persons | Deaths | HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI |
| White | 60 580 | 5917 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||||||
| Black | 1193 | 119 | 1.77 | 1.48–2.13 | 1.52 | 1.26–1.84 | 1.35 | 1.12–1.63 | 1.38 | 1.14–1.66 | 1.44 | 1.19–1.74 | 1.49 | 1.24–1.80 | 1.24 | 1.03–1.50 |
| Asian | 1964 | 116 | 0.98 | 0.81–1.18 | 0.87 | 0.72–1.05 | 0.88 | 0.73–1.06 | 0.82 | 0.68–0.99 | 0.85 | 0.71–1.03 | 0.88 | 0.73–1.06 | 0.86 | 0.71–1.03 |
| Other and unknown | 23 115 | 2609 | 0.99 | 0.95–1.04 | 1.03 | 0.98–1.08 | 1.03 | 0.98–1.08 | 1.05 | 1.00–1.10 | 1.01 | 0.96–1.06 | 1.03 | 0.98–1.08 | 1.05 | 1.00–1.11 |
| Heterogeneity | χ2(3)=38.4; P<0.001 | χ2(3)=23.2; P<0.001 | χ2(3)=13.3; P=0.004 | χ2(3)=20.0; P<0.001 | χ2(3)=18.3; P<0.001 | χ2(3)=20.8; P<0.001 | χ2(3)=12.5; P=0.006 | |||||||||
Abbreviations: CI=confidence interval, ER=oestrogen receptor, HER2=human epidermal growth factor 2 receptor, HR=hazard ratio, PR=progesterone receptor; SES=socio-economic status.
Cox proportional regression analyses of ethnicity.
Model 1 adjusted for age.
Model 2 adjusted for age, socioeconomic status, region of residence and comorbidity.
Model 3a adjusted for age, socioeconomic status, region of residence, comorbidity and stage (missing stage as a category).
Model 3b adjusted for age, socioeconomic status, region of residence, comorbidity and grade.
Model 3c adjusted for age, socioeconomic status, region of residence, comorbidity, and ER, PR and HER2 status.
Model 3d adjusted for age, socioeconomic status, region of residence, comorbidity and morphology.
Model 4 adjusted for age, socioeconomic status, region of residence, comorbidity, stage, grade, ER, PR and HER2 status, and morphology.