Figure 1.

Kaplan–Meier estimate of the survival function for the time to tumour progression for all 254 patients. The crosses indicate right-censored data whereby patients' tumours were stable at the last time of contact before being lost to follow-up. The median time to tumour progression is 37 months (95% CI: 32–52 months), given by the time at which the Kaplan–Meier estimate of the survival function is 0.5. The mean time to tumour progression is 51 months (95% CI: 45–57 months), calculated using a restricted upper time limit of 120 months.