Table 1b. Descriptive statistics for the BCVA, full-field ERG and EOG parameters evaluated in our RP patients' group and in the control group.
| Parameters mean±SD |
Retinitis pigmentosa patients
mean±SD |
Controls mean±SD | P-values (univariate ANOVA) | ||
|---|---|---|---|---|---|
| RP patients total | No-ME-RP subgroup | ME-RP subgroup | |||
| BCVA | |||||
| logMAR | 0.391±0.432 | 0.411±0.483 | 0.341±0.273 | 0.003±0.022 | <0.001* |
| Full-field ERG | |||||
| Dark-adapted 3.0 ERG | |||||
| A-wave amplitude (μV) | −43.02±60.99 | −54.81±67.70 | −14.20±22.72 | −237.17±75.36 | <0.001* |
| B-wave amplitude (μV) | 78.27±91.10 | 100.45±97.29 | 24.06±38.14 | 405.97±146.95 | <0.001* |
| Light-adapted 3.0 ERG | |||||
| A-wave amplitude (μV) | −13.58±15.71 | −16.24±17.55 | −7.09±6.64 | −46.07±30.92 | <0.001* |
| B-wave amplitude (μV) | 41.88±39.86 | 41.89±41.49 | 41.8638±36.71 | 201.42±64.43 | <0.001* |
| EOG | |||||
| Arden ratio | 1.64±0.74 | 1.79±0.84 | 1.32±0.31 | 2.46±0.38 | <0.001* |
| Dark-trough amplitude (μV) | 239.79±110.25 | 242.83±111.71 | 233.55±110.10 | 360.54±109.81 | <0.001* |
| Light-peak amplitude (μV) | 367.80±174.03 | 403.92±185.69 | 293.55±120.45 | 861.97±238.91 | <0.001* |
P-values of <0.05 are considered statistically significant and are marked with asterisk. Within the RP subgroups, ME-RP patients tend to have lower a- and b-wave amplitudes of the scotopic full-field ERG (P=0.030 and P=0.016, respectively), as well as lower Arden ratio (P=0.013) of the EOG when compared with no-ME-RP patients.