Table 1c. Descriptive statistics for the OCT and mfERG parameters evaluated in our RP patients' group and in the control group.
Parameters mean±SD |
Retinitis pigmentosa patients
mean±SD |
Controls mean±SD | P-values (univariate ANOVA) | ||
---|---|---|---|---|---|
Total | No-ME-RP subgroup | ME-RP subgroup | |||
OCT (μm) | |||||
Zone 1 | 262.88±90.25 | 231.09±51.37 | 342.50±104.83 | 260.31±26.75 | <0.001* |
Zone 2 | 298.55±57.70 | 284.20±47.18 | 341.04±57.52 | 317.69±12.13 | <0.001* |
Zone 3 | 251.30±36.02 | 247.78±36.97 | 272.86±33.97 | 271.30±23.79 | <0.001* |
PMA | 282.38±63.63 | 262.51±45.01 | 330.94±76.68 | 290.99±12.93 | <0.001* |
IS/OS line | 2502.77±1794.44 | 2354.26±1988.16 | 2824.56±1269.36 | 5984.89±103.56 | <0.001* |
mfERG | |||||
N1 amplitudes (nV/deg2) | |||||
Zone 1 | −21.11±15.83 | −19.71±16.94 | −24.44±12.59 | −60.95±15.58 | <0.001* |
Zone 2 | −12.19±9.18 | −11.66±10.13 | −13.46±6.41 | −34.70±7.31 | <0.001* |
Zone 3 | −5.30±3.88 | −4.79±4.09 | −6.53±3.08 | −17.35±3.82 | <0.001* |
PMA | −4.46±3.16 | −4.24±3.38 | −4.99±2.56 | −13.57±3.24 | <0.001* |
N1P1 amplitudes (nV/deg2) | |||||
Zone 1 | 44.11±26.29 | 42.34±29.29 | 48.36±17.09 | 136.98±32.18 | <0.001* |
Zone 2 | 21.84±14.68 | 20.79±15.89 | 24.36±11.29 | 74.71±15.70 | <0.001* |
Zone 3 | 8.64±7.01 | 8.50±7.30 | 8.96±6.46 | 35.73±7.90 | <0.001* |
PMA | 6.50±4.68 | 6.24±5.13 | 7.14±3.43 | 26.42±6.58 | <0.001* |
Descriptive statistics for the OCT readings (μm) and mfERG amplitudes (nV/deg2), evaluated in zones, presented for our RP patients' group and in the control group separately. For all examined locations, the retinal thickness, measured by OCT, was significantly thicker in the ME-RP subgroup when compared with the no-ME-RP subgroup (P≤0.003). This was, however, not the case for the IS/OS line length (P=0.272). The two RP subgroups did not differ from one another by means of mfERG response amplitudes (P≥0.098).