Table 1. Baseline parameters and treatment outcome after subthreshold micropulse laser and photodynamic therapy.
Treatment response | Complete resolution of SRF | CRT (μm) baseline Mean±SD | CRT (μm) after therapy Mean±SD | P-value | Decrease in CRT (μm) Mean±SD | Increase in BCVA of 1 or more lines | BCVA (LogMAR) baseline Mean±SD | BCVA (LogMAR) after therapy | P-value | Increase in BCVA (LogMAR) Mean±SD | |
---|---|---|---|---|---|---|---|---|---|---|---|
All patients (n=100) | 67 of 100 (67%) | 27 of 100 (27%) | 418±121 | 311±94** | P<0.001** Wilcoxon's signed-rank test | -106±136 | 50 of 100 (50%) | 0.37±0.24 | 0.31±0.25** | P=0.001** Wilcoxon's signed-rank test | −0.059±0.168 |
SML (n=42) | 33 of 42 (79%)* | 15 of 42 (36%) | 445±153 | 297±95** | P<0.001** Wilcoxon's signed-rank test | −148±163* | 23 of 42 (55%) | 0.39±0.24 | 0.31±0.27** | P=0.003** Wilcoxon signed-rank test | −0.081±0.167 |
PDT (n=58) | 34 of 58 (59%)* | 12 of 58 (21%) | 398±88 | 322±93** | P<0.001** Wilcoxon's signed-rank test | −76±104* | 27 of 58 (47%) | 0.35±0.24 | 0.31±0.24 | P=0.077 Wilcoxon's signed-rank test | −0.043±0.169 |
P-value* | P=0.036* χ2 test | P=0.095 χ2 test | P=0.242 Mann–Whitney U-test | P=0.041* Mann–Whitney U-Test | P=0.418 χ2 test | P=0.360 Mann–Whitney U-test | P=0.349 Mann–Whitney U-test |
**Statistically significant difference before and after therapy.
*Statistically significant difference between the SML and the PDT group.