TABLE 1.
Denver Postinjury Multiple Organ Failure Score
| Organ System | Grade 0 | Grade 1 | Grade 2 | Grade 3 |
|---|---|---|---|---|
| Pulmonary | ||||
| PaO2/FiO2 ratio | >250 | 250–200 | 200–100 | ≤100 |
| Renal | ||||
| Creatinine (mg/dL) | ≤1.8 | 1.9–2.5 | 2.51–5.0 | >5.0 |
| Creatinine (μmol/L) | <159 | 160–221 | 222–442 | >442 |
| Hepatic | ||||
| Bilirubin (mg/dL) | ≤2.0 | 2.0–4.0 | 4.1–8.0 | >8.0 |
| Bilirubin (μmol/L) | <34 | 34–68 | 69–137 | >137 |
| Cardiac | No inotropes | Only one inotrope at a small dosea | Any inotrope at moderate dose or >1 agent, all at small dosesa | Any inotrope at large dose or >2 agents at moderate dosesa |
| Small | Moderate | Large | |
|---|---|---|---|
| Milrinone | <0.3 | 0.4–0.7 | >0.7 |
| Vasopressin | <0.03 | 0.03–0.07 | >0.07 |
| Dopamine | <6 | 6–10 | >10 |
| Dobutamine | <6 | 6–10 | >10 |
| Epinephrine | <0.06 | 0.06–0.15 | >0.15 |
| Norepinephrine | <0.11 | 0.11–0.5 | >0.5 |
| Phenylephrine | <0.6 | 0.6–3 | >3 |
a
Inotrope doses (in μg/(kg min)):
a
Need for inotropes more than dopamine .× μg/(kg min).
b
PAR: pressure-adjusted heart rate. PAR = heart rate × central venous pressure/mean arterial blood pressure.