Table 3. Logistic regression analysis of rs190982 polymorphisms.
| Model | Total samplea | ApoE ε4 carriersb | ApoE ε4 non-carriersb | ||||
|---|---|---|---|---|---|---|---|
| OR(95%CI) | P | P for APOE interaction | OR(95%CI) | P | OR(95%CI) | P | |
| rs190982 | |||||||
| Dom | 1.001(0.835-1.200) | 0.993 | 0.734 | 1.062(0.710-1.588) | 0.771 | 0.986(0.804-1.209) | 0.890 |
| Rec | 0.737(0.388-1.397) | 0.349 | 0.208 | 1.441(0.425-4.881) | 0.557 | 0.551(0.243-1.248) | 0.153 |
| Add | 0.980(0.830-1.156) | 0.810 | 0.534 | 1.082(0.758-1.544) | 0.663 | 0.954(0.790-1.151) | 0.622 |
Abbreviations: ApoE ε4 carrier, subjects who contain 1 or 2 ε4 alleles; ApoE ε4 non-carriers, subjects who do not contain ε4 allele; OR, odds ratios; CI, confidence interval; Dom, dominant model; Rec, recessive model; Add, additive model.
a
Adjusted for age, gender and APOE ε4 status,
b
Adjusted for age and gender.