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. 2016 May 9;7(26):39184–39196. doi: 10.18632/oncotarget.9258

Figure 7. Decreased dendritic spine density after Prrt2 knockdown.

Figure 7

A. Dendritic spines were imaged at P21 and P30 in brains electroporated in utero with control or Prrt2 shRNA along with EGFP constructs at E14.5. Lower spine densities for Prrt2 shRNA-expressing pyramidal neurons were observed on representative dendrites at both P21 and P30. B. Statistical analysis of spine density of dendrites at P14, P21 and P30. There was no significant difference between control and Prrt2 shRNA-expressing groups at P14. Significant decreases in spine density for Prrt2 shRNA-expressing cells were observed at P21 and P30. *: p < 0.05.