Table 1. Clinicopathological summary of endometrial papillary proliferations.
Case | Clinical feature | Histopathological feature | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Age | MP | HRT | Previousgynecologicalhistory | Clinicalpresentation | Currentstatus | Type ofspecimen | Pattern ofpapillaryproliferation | Volume ofpapillaryproliferation | Metaplasticepithelialchange | Relation withEM hyperplasia or carcinoma | |
1 | 57 | Yes | No | Cervical HSIL | No symptom | NED | Hysterectomy | Simple | <10% of entire EM | M, C, E, P | No |
2 | 65 | Yes | No | No | Vaginal bleeding, EM polyp | NED | Curettage | Complex | 80% of EM polyp | M, E | Subsequent atypical hyperplasia/EIN in hysterectomy specimen (after 4 months) |
3 | 64 | Yes | Yes | No | Vaginal bleeding, Thickened EM | NED | Curettage | Simple | <10% of entire EM | M, C, E | Subsequent hyperplasia without atypia in hysterectomy specimen (after 3 months) |
4 | 70 | Yes | No | EM hyperplasia without atypia | Vaginal spotting, Thickened EM | NED | Hysterectomy | Simple | <10% of entire EM | M, E | Coexistent well-differentiated EM carcinoma in hysterectomy specimen |
C: ciliated cell metaplasia, E: eosinophilic cell change, EIN: endometrioid intraepithelial neoplasia, EM: endometrium, HRT: hormone replacement therapy, HSIL: high-grade squamous intraepithelial lesion, M: mucinous metaplasia, MP: menopause, NED: no evidence of disease, P: papillary syncytial metaplasia.