Table 2. Demographic and clinical data (females).
| Variable | Control | Patients (n = 385) | P | |||
|---|---|---|---|---|---|---|
| (n = 227) | CAS1 | CAS2 | CAS3 | CAS4 | ||
| (n = 170) | (n = 94) | (n = 105) | (n = 16) | |||
| Age (yr) | 43.3 ± 10.4 | 62.5 ± 9.0 | 65.8 ± 8.6 | 67.0 ± 8.5 | 70.9 ± 5.9 | <0.001 |
| UA (umol/L) | 283.0 ± 60.0 | 323.9 ± 84.4 | 321.0 ± 85.6 | 325.2 ± 95.4 | 375.3 ± 79.4 | <0.001 |
| TC (mmol/L) | 4.5 ± 0.8 | 4.9 ± 1.1 | 5.1 ± 1.3 | 5.0 ± 1.4 | 5.5 ± 1.4 | <0.001 |
| TG (mmol/L) | 1.2 (0.9, 1.7) | 1.9 (1.4, 2.7) | 1.6 (1.2, 2.4) | 1.7 (1.3, 2.2) | 2.2 (1.9, 2.8) | <0.001 |
| HDL-C (mmol/L) | 1.6 ± 0.3 | 1.2 ± 0.3 | 1.2 ± 0.2 | 1.2 ± 0.3 | 1.2 ± 0.2 | <0.001 |
| LDL-C (mmol/L) | 2.7 ± 0.7 | 2.8 ± 0.8 | 2.9 ± 0.9 | 2.8 ± 1.0 | 3.3 ± 1.5 | 0.073 |
| apoA (g/L) | 1.6 ± 0.3 | 1.3 ± 0.2 | 1.3 ± 0.3 | 1.2 ± 0.3 | 1.2 ± 0.2 | <0.001 |
| apoB (g/L) | 0.8 ± 0.1 | 0.9 ± 0.2 | 0.9 ± 0.2 | 0.9 ± 0.3 | 1.0 ± 0.3 | <0.001 |
| Lp(a) (mg/L) | 116.0 (70.0, 228.0) | 122.0 (57.8, 334.8) | 199.0 (95.5, 381.8) | 190.0 (97.0, 408.5) | 421.0 (168.8, 708.0) | <0.001 |
| HCY (umol/L) | 7.1 (4.3, 9.7) | 16.0 (12.0, 19.4) | 17.0 (12.4, 18.9) | 16.0 (13.0, 20.3) | 19.3 (16.5, 21.7) | <0.001 |
| TBil (umol/L) | 11.5 (8.9, 14.5) | 11.3 (7.9, 14.0) | 9.9 (7.5, 13.1) | 9.1 (7.1, 12.4) | 6.7 (5.6, 11.7) | <0.001 |
| DBil (umol/L) | 2.9 (2.3, 3.7) | 3.7 (2.4, 4.7) | 3.5 (2.5, 4.5) | 3.2 (2.3, 4.1) | 2.9 (2.0, 3.7) | 0.011 |
| IBil (umol/L) | 8.5 (6.6, 10.8) | 7.7 (5.2, 10.0) | 6.1 (4.5, 9.1) | 6.1 (3.5, 7.8) | 4.9 (2.6, 8.3) | <0.001 |
| GGT (IU/L) | 15.0 (11.0, 22.0) | 32.0 (20.0, 59.3) | 30.5 (20.0, 49.8) | 32.0 (20.5, 63.0) | 44.5 (28.5, 75.5) | <0.001 |
Normally distributed data are presented as means ± standard deviation (SDs) and skewed data as medians (with interquartile range). Differences among groups were compared using the Kruskal-Wallis H test or one-way ANOVA depending on the nature of data distribution. For abbreviations, see Table 1.