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. 2016 Jun 7;7(26):39302–39315. doi: 10.18632/oncotarget.9909

Figure 5. EPCs-hTERT-induced changes in cavernous fibrosis and TGF-β1 signaling pathway expression.

Figure 5

(A) Masson's trichrome staining: collagen fibers are stained blue, and smooth muscle are stained red (100×). (B) Semi-quantitative evaluation of collagen/smooth muscle ratios. (C) Western blotting was used to detect the expression of TGF-β1, Smad2/3 and p-Smad2/3 in penile tissues of the five groups. (D) Bar graphs show the densitometric ratios of TGF-β1 toβ-actin and phosphorylated Smad2/3 to total Smad2/3. *P<0.05 vs. normal control group, # P<0.05 vs. DMED group, & P<0.05 vs. EPCs group and EPCs-control group.