Table 1. Clinical or laboratory characteristics and the pituitary hormone levels of study participants.
| Healthy control (n = 60) |
Isolated hypertriglyceridemia (n = 30) |
p value | |
|---|---|---|---|
| Age (yr), mean (SD) | 51.07 (3.97) | 51.43 (4.75) | 0.717 |
| SBP (mmHg), mean (SD) | 123.08 (9.69) | 121.79 (12.94) | 0.597 |
| DBP (mmHg), mean (SD) | 76.18 (6.45) | 76.60 (8.35) | 0.792 |
| FPG (mmol/L), mean (SD) | 5.45 (0.29) | 5.54 (0.45) | 0.372 |
| HbA1c (%), mean (SD) | 5.60 (0.30) | 5.60 (0.24) | 0.916 |
| BMI (kg/m2), mean (SD) | 22.95 (2.48) | 26.43 (3.28) | <0.001 |
| WC (cm), mean (SD) | 84.68 (6.16) | 89.76 (9.86) | 0.014 |
| WHR, mean (SD) | 0.88 (0.05) | 0.93 (0.06) | <0.001 |
| TC (mmol/L), mean (SD) | 4.07 (0.89) | 4.32 (0.83) | 0.207 |
| TG (mmol/L), mean (SD) | 1.00 (0.32) | 2.90 (1.42) | NA |
| LDL-C (mmol/L), mean (SD) | 2.44 (0.65) | 2.17 (0.67) | 0.070 |
| Pituitary-thyroid axis | |||
| TSH (mIU/L),median (IQR) | 1.43 (1.16) | 2.17 (1.47) | 0.001 |
| FT3 (pmol/L), mean (SD) | 5.18 (0.58) | 5.06 (0.75) | 0.419 |
| FT4 (pmol/L), mean (SD) | 17.32 (2.20) | 16.29 (1.82) | 0.030 |
| Pituitary-gonadal axis | |||
| FSH (mIU/mL), mean (SD) | 6.16 (1.84) | 7.76 (3.21) | 0.015 |
| LH (mIU/mL), mean (SD) | 4.96 (1.35) | 6.17 (1.90) | 0.003 |
| T (ng/mL), mean (SD) | 6.47 (2.03) | 4.62 (1.44) | <0.001 |
| Pituitary-adrenal axis | |||
| ACTH (pg/mL), mean (SD) | 13.41 (6.76) | 9.03 (3.14) | <0.001 |
| COR (nmol/L), mean (SD) | 405.15 (153.34) | 480.83 (130.21) | 0.023 |
The groups were compared using the Student's t-tests or the Mann-Whitney test. P values less than 0.05 were considered statistically significant.
Abbreviations: NA, not applicable; SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HbA1c, hemoglobinA1c; BMI, body mass index; WC, waist circumference; WHR, waist hip ratio; TC, total cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; TSH, thyroid-stimulating hormone; FT3, free triiodothyronine; FT4, free thyroxine; FSH, follicle-stimulating hormone; LH, luteinizing hormone; T, testosterone; ACTH, adrenocorticotropin; COR, cortisol.