Figure 4. CHOP or XBP1 deficiency partially rescues the semiactivated phenotype of Slfn2eka/eka CD8+ T cells.
A. Flow cytometry analysis of the staining for CD122 (IL-2Rβ) and CD44 in splenic CD8+ T cells from C57BL6/J, Slfn2eka/eka, CHOP−/− /Slfn2eka/eka or XBP1lox/lox /Slfn2eka/eka mice (n =9). Numbers in quadrants indicate percent cells in each. B., C. Flow cytometry analysis for the expression levels of CD62L (upper panel) and IL-7Rα (CD127) (lower panel) on surface of both CD8+CD44lo (left) and CD8+CD44hi (right) T cells from the C57BL6/J, Slfn2eka/eka, CHOP−/− /Slfn2eka/eka (B) or XBP1lox/lox /Slfn2eka/eka mice (C) (n=9).