Table 1. Demographic and clinical characteristics of RHAMM in primary non-small cell lung cancer.
| RHAMM | ||||
|---|---|---|---|---|
| Total n = 156 | Negative staining n = 67 | Positive staining n = 89 | p value | |
| Age (Median), IQR | ||||
| 69, IQR (63–75) | 68, IQR (61–73) | 70, IQR (64–77) | 0.157 | |
| Sex | ||||
| Female | 91 | 38 (42%) | 53 (58%) | 0.722 |
| Male | 65 | 29 (45%) | 36 (55%) | |
| Smoking | ||||
| Yes | 127 | 58 (46%) | 69 (54%) | 0.150 |
| No | 29 | 9 (31%) | 20 (69%) | |
| Histology | ||||
| Adeno | 127 | 59 (46%) | 68 (54%) | 0.180 |
| Squamous | 22 | 6 (27%) | 16 (73%) | |
| Other (large cell, pleomorphic carcinoma) | 7 | 2 (29%) | 5 (71%) | |
| Differentiation status | ||||
| Well | 32 | 20 (62.5%) | 12 (37.5%) | 0.030 |
| Moderate | 78 | 30 (38%) | 48 (62%) | (significant) |
| Poor | 36 | 12 (33%) | 24 (67%) | |
| Missing/unknown | 10 | 5 | 5 | |
| Pathological ‘T’ stages | ||||
| T1 | 89 | 48 (54%) | 41 (46%) | 0.009 |
| T2 | 53 | 15 (28%) | 38 (72%) | (significant) |
| T3 | 3 | 0 (0%) | 3 (100%) | |
| T4 | 11 | 4 (36%) | 7 (64%) | |
| Pathological ‘N’ status | ||||
| Nx/No | 130 | 59 (45%) | 71 (55%) | 0.169 |
| N+ | 26 | 8 (31%) | 18 (69%) | |
IQR: interquartile range; Adeno: lung adenocarcinoma; Squamous: Squamous cell carcinoma; Nx, patients in whom the regional lymph nodes cannot be assessed; No: no regional metastases detected; N+: regional lymph node metastases.