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a. Trans-well assay indicated that knockdown of SCD1 in H1650 significantly suppressed the invasive ability of cells, whereas overexpression of SCD1 in HEK293 remarkably enhance that ability of cells. b. and c. The exrepssion level of SCD1 positively correlated with cell migration. d. In vivo study showed that tumor weight and size is much lighter and smaller in SCD1 knockdown H1650 cells.
