Figure 8. mRNA expression of genes relating to apoptosis, cell cycle arrest, nucleotide excision repair (NER) and DNA mismatch repair in response 5 μM Nutlin-3 or 0.5 μM RG7388 for 6 hours relative to DMSO solvent control.
A. A2780, B. IGROV-1 and C. OAW42, *, p < 0.05; **, P < 0.01. Data are presented as mean ± standard error of mean (SEM) of three independent repeats.