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. 2016 May 23;7(26):40174–40188. doi: 10.18632/oncotarget.9559

Figure 10. Suppression of integrin αvβ3/FAK signaling abrogates BKCa-enhanced proliferation and migration.

Figure 10

A. Western blot analysis of FAK and p-FAK(397) in BKCa or Vector transfected prostate cancer PC3 cells treated with NS1619 (30 μM), IBTX (100 nM), LM609 (10 μg/ml) or Y15 (10μM) for 24 hr. B. MTT assay showed that BKCa-enhanced cell viability was abrogated by inhibition of the αvβ3/FAK signaling. C. Migration assay revealed that BKCa-enhanced cell migration was abrogated by inhibition of the αvβ3/FAK signaling.