Table 1. Clinical characteristics of patients grouped by the CD4/CD8 ratio (cut off 1.0).

Patient characteristics	n = 234	CD4:CD8 ratio
		< 1	> 1	p
Age (years)	61 (20–86)
Gender (%)
Male	159 (67.95%)
Female	75 (32.05%)
Binet stage (%)
A/B	167 (71.37%)	32	135	0.039
C	67 (28.63%)	22	45
IGHV (%) n = 197
Mutated	122 (61.93%)	32	90	0.298
Unmutated	75 (38.07%)	14	61
CD38 (%) n = 225
Positive (> 30%)	48 (21.33%)	16	32	0.054
Negative (< 30%)	177 (78.67%)	35	142
ZAP70 (%) n = 202
Positive (> 20%)	88 (43.56%)	16	72	0.098
Negative (< 20%)	114 (56.44%)	33	81
With TP53 mutation or del (17 p)	23 (13.69%)	8	15	0.105
Without TP53 mutation or del (17 p)	145 (86.31%)	28	117