Table 4. Increased abundance of ADAM9 following tissue injury and sterile inflammation.
| GEO ID | A vs B | Avg A-Avg B | Avg A/Avg B | P value |
|---|---|---|---|---|
| GSE34608 | Sarcoidosis VS Control | 56.4 | 1.9 | < 0.0001 |
| Tuberculosis VS control | 56.9 | 1.9 | < 0.0001 | |
| GSE11375 | Survived VS Control | 17.7 | 1.2 | 0.0367 |
| Died VS Control | 45.2 | 1.6 | 0.0226 | |
| Survived VS Died | 27.5 | 1.3 | 0.0473 | |
| GSE15072 | HD VS Healthy | 545.6 | 7.6 | < 0.0001 |
| CKD VS Healthy | 94.3 | 2.1 | 0.0359 | |
| GSE28750 | Post surgery VS Healthy | 153.2 | 5.1 | < 0.0001 |
| Sepsis VS Healthy | 281.8 | 8.5 | < 0.0001 | |
| GSE30174 ** | Healthy VS Baseline | 35.8 | 1.1 | 0.7243 |
| Healthy VS 1h EBRT | -91.3 | 0.9 | 0.4727 | |
| Healthy VS D7 EBRT | 236.5 | 1.4 | 0.1419 | |
| Healthy VS D14 EBRT | 455.8 | 1.7 | 0.0068 | |
| Healthy VS D21 EBRT | 643.8 | 2.0 | 0.0021 | |
| Healthy VS D42 EBRT | 272.1 | 1.4 | 0.2150 | |
| Healthy VS 1 mo Post Tx | 85.8 | 1.1 | 0.5678 | |
| GSE32575 | Obese before surgery VS control | 34.1 | 1.3 | < 0.0001 |
| Obese post surgery VS control | 19.0 | 1.2 | 0.0001 | |
| GSE5580 | TP mono VS HC mono | 247.1 | 1.7 | 0.0070 |
| TP Leukocyte VS HC Leukocyte | 233.2 | 2.9 | 0.0006 | |
| TP T cell VS HC T cell | 57.9 | 3.0 | 0.0175 |
Note : Avg = average abundance of ADAM9 within a given group. Statistical significance was determined using Mann-Whitney U test. ** This dataset was tested by One-way ANOVA and Dunnett’s multiple comparisons test, P value summary = 0.0042.