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. Author manuscript; available in PMC: 2017 Nov 9.
Published in final edited form as: Cells Tissues Organs. 2016 Nov 9;202(3-4):169–179. doi: 10.1159/000444671

Figure 2. Growth Factor Signalling in Skeletal Muscle Regeneration.

Figure 2

The microenvironment surrounding the satellite cell (SC) niche plays a key role in repair of skeletal muscle damage. Resident immune cells, extracellular matrix (ECM), and capillary and neural networks compose this niche. This schematic describes a simplified process by which essential growth factors (FGF, TGFβ, IGF, and PDGF) are supplied to stimulate and regulate SCs.