Table 2. Group Means for Overall Response Latency in List-DMS in Milliseconds.
Ketamine (ms) | AZD6765 (ms) | CP101,606 (ms) | BMT-108908 (ms) | |
---|---|---|---|---|
Vehicle (SEM) | 2405 (82.4) | 2459 (72.0) | 2526 (70.7) | 2443 (80.3) |
0.10 mg/kg (SEM) | n.t. | n.t. | n.t. | 2381 (171.6) |
0.30 mg/kg (SEM) | 2501(137.2) | n.t. | 2382 (135.7) | 2574 (82.8) |
0.56 mg/kg (SEM) | 2521(192.7) | n.t. | n.t. | n.t. |
1.00 mg/kg (SEM) | 2386 (215.1) | 2460 (107.3) | 2604 (107.5) | 2798 (65.42)* |
1.70 mg/kg (SEM) | 2994 (49.2)** | n.t. | n.t. | n.t. |
3.00 mg/kg (SEM) | n.t. | 2563 (140.2) | 2557 (122.8) | 2744 (94.78) |
5.60 mg/kg (SEM) | n.t. | 2456 (215.3) | 2431 (142.7) | n.t. |
10.00 mg/kg (SEM) | n.t. | n.t. | 2802 (98.7) | n.t. |
Abbreviation: n.t., not tested. * and ** indicate performance differed from vehicle at p<0.05 and p<0.01 levels, respectively, using Holm–Sidak test.