Table 3. Group Means for List-DMS Percent Completion.
Ketamine | AZD6765 | CP101,606 | BMT-108908 | |
---|---|---|---|---|
15 min PT | 30 min PT | 30 min PT | 30 min PT | |
Vehicle (SEM) | 98.4% (0.5%) | 97.0% (0.7%) | 96.9% (1.1%) | 96.4% (1.7%) |
0.10 mg/kg (SEM) | n.t. | n.t. | n.t. | 94.8% (4.7%) |
0.30 mg/kg (SEM) | 75.4% (12.8%) | n.t. | 95.8% (1.8%) | 96.2% (2.4%) |
0.56 mg/kg (SEM) | 74.0% (8.2%) | n.t. | n.t. | n.t. |
1.00 mg/kg (SEM) | 65.6% (9.8%)* | 84.5% (11.8%) | 76.2% (8.8%) | 95.1% (1.8%) |
1.70 mg/kg (SEM) | 43.2% (12.5%)** | n.t. | n.t. | n.t. |
3.00 mg/kg (SEM) | n.t. | 94.1% (3.3%) | 83.7% (7.8%) | 90.9% (6.8%) |
5.60 mg/kg (SEM) | n.t. | 55.8% (14.2%)** | 66.7% (12.3%)* | n.t. |
10.00 mg/kg (SEM) | n.t. | n.t. | 70.4% (9.2%) | n.t. |
Abbreviation: n.t., not tested. * and ** indicate performance differed from vehicle at p<0.05 and p<0.01 levels, respectively, using Holm–Sidak test.