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. 2016 Nov 30;11(11):e0166359. doi: 10.1371/journal.pone.0166359

Table 6. Risk factors for in-hospital death.

Variable Univariate analysis Multivariate analysis
RR 95% CI p-valuea Adj. RR 95% CI p-valuea
Age (years) <70 1 - - 1 - -
70–80 2.12 0.611–7.35 0.236 1.99 0.57–6.96 0.281
>80 5.69 1.77–18.3 0.004 5.08 1.56–16.5 0.007
Sex Male 1 - - 1 - -
Female 0.99 0.57–1.73 0.981 1.17 0.67–2.04 0.587
Living condition At home 1 - - 1 - -
Institutionalized 1.82 0.85–3.93 0.124 0.61 0.25–1.45 0.264
Charlson Comorbidity Index ≥1 4.69 2.52–8.75 <0.001 4.94 2.48–9.84 <0.001
Number of diagnoses at admission
≤5 1 - - 1 - -
6–8 1.71 0.73–3.99 0.216 0.95 0.41–2.35 0.924
≥9 1.72 0.74–3.97 0.201 0.91 0.37–2.21 0.839
Number of drugs at admission
≤2 1 - - 1 - -
3–5 1.60 0.64–3.99 0.308 1.12 0.46–2.68 0.807
6–7 1.57 0.58–4.23 0.370 0.97 0.37–2.55 0.959
≥8 1.66 0.66–4.20 0.282 0.73 0.27–1.93 0.530
Hospital stay (days), for each additional week 1.04 0.76–1.42 0.791 0.85 0.57–1.27 0.432
Intervention (checklist) 0.66 0.37–1.15 0.142 0.73 0.43–1.26 0.269

RR: risk ratios. CI: confidence interval. Adj. RR: adjusted risk ratios for all variables listed.

aPoisson regression models with a robust error variance, Likelihood Ratio Test.