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. 2016 Nov 30;11(11):e0166318. doi: 10.1371/journal.pone.0166318

Fig 1. Antiviral activity against Kikwit variant of Ebola virus.

Fig 1

Vero E6, Hep G2, HeLa, or Huh 7 cells were treated 1 h with toremifene citrate (A), lamivudine (B), or zidovudine (C). Two-fold dilutions of the drugs were tested in a 4- to 8-point dose-response curve. Then cells were infected at a multiplicity of infection (MOI) of 1 for 48 h. Toremifene citrate was used as a positive control. Antiviral activity is shown in blue and cytotoxicity is shown in red. The experiment was run on duplicate plates with triplicate wells per dose (mean ± SD; n = 3). Representative graphs from 1 to 4 independent experiments are shown.