Table 3.

Best response rates using RECIST 1.1, density criteria, and short axis criteria of assessment in patients with single changes in density and short axis in tumor

Response	RECIST1.1			Density Criteria			Short Axis Criteria
	No. of patients (%)	Median PFS (months)	P	No. of patients (%)	Median PFS (months)	P	No. of Patients (%)	Median PFS (months)	P
Patients with single change in density			0.235†			0.419‡
PR	0 (0)	–		15 (68.2)	9.4
SD	21 (95.5)	8.5		0 (0)	–
PD	1 (4.5)	15.0		7 (31.8)	7.9
Patients with single change in short axis									0.004‡
PR	0 (0)	–					7 (77.8)	11.0
SD	9 (100)	10.3					0 (0)	–
PD	0 (0)	–					2 (22.2)	5.8

^† SD versus PD.

^‡ PR versus PD.

RECIST, Response Evaluation Criteria in Solid Tumors; PD, progressive disease; PFS, progression‐free survival; PR, partial response; SD, stable disease