Table 1.

Compounds identified from ginseng extract

No .	Name	RT (min )	Formul a	MW (Da)	Measu red (Da)a	Err or (pp m)	Main MS/MS fragment ions	Ref .
1	Majonoside R1/isomer	3.21 1	C42H72 O15	816.48 72	815.48 15	2.5	653.4313 [M−H−Glc]−; 635.4169 [M−H−Glc−H2O]−; 491.3742 [M−H−2Glc]−	27
2	Notoginsenoside N1/isomer	3.64 3	C48H82 O19	962.54 5	961.54 05	3.4	799.4956 [M−H−Glc]−;781.4812 [M−H−Glc−H2O]−	27
3	Majonoside R1/isomer	6.31 1	C42H72 O15	816.48 72	815.48 00	0.7	653.4299 [M−H−Glc]−; 635.4299 [M−H−Glc−H2O]−; 491.3761 [M−H−2Glc]−	27
4	20-glc-Rf	7.43 2	C48H82 O19	962.54 50	961.53 85	1.4	799.4893 [M−H−Glc]−; 637.4316 [M−H−2Glc]−; 475.3767 [M−H−3Glc]−	23, 25
5	Notoginsenoside R1	7.85 1	C47H80 O18	932.53 45	931.52 75	0.8	799.4871 [M−H−Glc]−; 637.4315 [M−H−Araf−Glc]−; 475.3794 [M−H−Araf−2Glc]−	23, 28
6	Ginsenoside Rg1	8.58 5	C42H72 O14	800.49 22	799.48 68	2.4	637.4321 [M−H−Glc]−; 475.3798 [M−H−2Glc]−	23, 28
7	Ginsenoside Re	8.64 5	C48H82 O18	946.55 01	945.54 58	3.2	799.4918 [M−H−Rha]−; 783.4956 [M−H−Glc]−; 637.4348 [M−H−Rha−Glc]−; 475.3806 [M−H−Rha−Glc]−	23, 28
8	Notoginsenoside A/isomer	9.92 3	C54H92 O24	1124.5 979	1123.5 901	0	961.5431 [M−H−Glc]−; 799.4781 [M−H−2Glc]−; 781.4802 [M−H−2Glc−H2O]−	27
9	Ginsenoside Rf	13.2 36	C42H72 O14	800.49 22	799.48 19	−3.1	637.432 [M−H−Glc]−; 475.3768 [M−H−2Glc]−	23, 28
10	Bu-Rg1	13.3 57	C46H76 O15	868.51 84	867.51 34	3.2	799.4899 [M−H−Bu]−; 637.4337 [M−H−Bu−Glc]−; 475.3741 [M−H−Bu−2Glc]−	22
11	Ginsenoside Ra3	13.8 98	C59H100 O27	1240.6 452	1239.6 330	−3.5	1107.6207 [M−H−Xyl]−; 945.5357 [M−H−Xyl−Glc]−; 783.5173 [M−H−Xyl−2Glc]−; 621.4370 [M−H−Xyl−3Glc]−; 459.3882 [M−H−Xyl−4Glc]−	28
12	Notoginsenoside Fa	13.9 64	C59H100 O27	1240.6 452	1239.6 319	−4.4	1107.5786 [M−H−Xyl]−; 945.5450 [M−H−Xyl−Glc]−; 783.4880 [M−H−Xyl−2Glc]−; 621.4380 [M−H−Xyl−3Glc]−; 459.3845 [M−H−Xyl−4Glc]−	24
13	Notoginsenoside R2	14.5 32	C41H70 O13	770.48 16	769.47 20	− 2.3	637.4273 [M−H−Xyl]−; 475.3757 [M−H−Xyl−Glc]−	23, 28
14	Ginsenoside Rg2	16.3 16	C42H72 O13	784.49 73	783.48 70	−3.2	637.4311 [M−H−Rha]−; 475.3781 [M−H−Rha−Glc]−	23, 28
15	Ginsenoside Rh1	16.5 47	C36H62 O9	638.43 94	637.43 30	1.4	475.3765 [M−H−Glc]−	23, 28
16	Bu-Re	16.8 54	C52H86 O19	1014.5 763	1013.5 708	2.3	945.5451 [M−H−Bu]−; 799.4853 [M−H-Bu−Rha]−; 637.4331 [M−H-Bu−Rha−Glc]−; 475.3772 [M−H-Bu−Rha−2Glc]−	22
17	Ginsenoside Ra1	17.3 41	C58H98 O26	1210.6 346	1209.6 272	0.3	1077.6158 [M−H−Xyl]−; 945.5423 [M−H−Xyl−Arap]−; 783.4917 [M−H−Xyl−Arap−Glc]−; 765.4602 [M−H−Xyl−Arap−Glc−H2O] −; 621.4410 [M−H−Xyl−Arap−2Glc]−; 459.3818 [M−H−Xyl−Arap−3Glc]−	28
18	Bu-Rf	17.6 88	C46H76 O15	868.51 84	867.51 13	0.8	799.5486[M−H−Bu]−; 637.4282 [M−H−Bu−Glc]−; 475.3801 [M−H−Bu−2Glc]−	22
19	Ginsenoside Rb1	18.1 90	C54H92 O23	1108.6 029	1107.5 911	−3.6	945.5507 [M−H−Glc]−; 783.4896 [M−H−2Glc]−; 621.4381 [M−H−3Glc]−; 459.3838 [M−H−4Glc]−	23, 28
20	Malonyl-Rb1	20.3 06	C57H94 O26	1194.6 033	1193.5 993	2.8	1107.6072 [M−H−mal]−; 945.5593 [M−H−mal−Glc]−; 783.4674 [M−H−mal−2Glc]−; 765.4901 [M−H−mal-2Glc−H2O]−; 621.4435 [M−H−mal−3Glc]−	23, 28
21	Ginsenoside Rc	20.7 34	C53H90 O22	1078.5 924	1077.5 846	0	945.0000 [M−H−Araf]−; 783.0000 [M−H−Araf−Glc]−; 621.0000 [M−H−Araf−2Glc]−; 459.3812 [M−H−Araf−3Glc]−	23, 28
22	Ginsenoside Ro	20.9 29	C48H76 O19	956.49 81	955.47 36	−1.7	955.4828 [M−H]−; 793.4456 [M−H−Glc]−; 713.427[M−H−Glc−CO2−H2 O]−; 613.3784 [M−H-2Glc−H2O]−; 569.3766 [M−H−2Glc−CO2−H2O]−; 455.3549 [M−H-3Glc−Acid]−	23, 28
23	Ginsenoside Ra2	21.7 08	C58H98 O26	1210.6 346	1209.6 202	1.7	1077.6158 [M−H−Xyl]−; 945.5381 [M−H−Xyl−Araf]−; 783.4853 [M−H−Xyl−Araf−Glc]−; 765.4739 [M−H−Xyl−Araf−Glc−H2O] −; 621.4294 [M−H−Xyl−Araf−Glc−H2O] −; 459.3787 [M−H−Xyl−Araf−3Glc]−	28
24	Ginsenoside F1	23.5 59	C36H62 O9	638.43 94	637.43 39	3.6	475.3816 [M−H−Glc]−	28
25	Malonyl-Rc	23.8 07	C56H92 O25	1164.5 928	1163.5 887	2.7	1119.5898 [M−H−CO2]−; 1077.577 [M−H−mal]−; 945.5308 [M−H−mal-Araf]−; 783.4829 [M−H−mal-Araf−Glc]−; 621.4227 [M−H−mal-Araf−2Glc]−; 459.3813 [M−H−mal-Araf−3Glc]−	23, 28
26	Malonyl-Rb2	23.9 27	C56H92 O25	1164.5 928	1163.5 867	1.0	1119.5893 [M−H−CO2]−; 1077.5760 [M−H−mal-Arap]−; 945.5363 [M−H−mal-Arap]−; 783.4904 [M−H−mal-Arap−Glc]−; 621.4354 [M−H−mal-Arap−2Glc]−	23, 28
27	Malonyl-Ra1/ Malonyl-Ra2	24.5 01	C61H100 O29	1296.6 350	1295.6 299	1.7	1209.6272 [M−H−mal]−; 1077.6158 [M−H−mal−Xyl]−; 945.5423 [M−H−mal−Xyl−Ara]−; 783.4917[M−H−mal−Xyl−A ra−Glc]−; 765.4602 [M−H−mal]−Xyl−Ara−Glc− H2O]−; 621.4410[M−H−mal]−Xyl− Ara−2Glc]−; 459.3818[M−H−mal−Xyl−A ra−3Glc]−	28
28	Ginsenoside Rb2	25.0 78	C53H90 O22	1078.5 824	1077.5 761	0.9	945.5345 [M−H−Arap]−; 783.4844 [M−H−Arap−Glc]−; 621.4313 [M−H−Arap−2Glc]−; 459.3813 [M−H−Arap−3Glc]−	23, 28
29	Ginsenoside Rb3	26.7 16	C53H90 O22	1078.5 924	1077.5 846	0	945.0000 [M−H−Xyl]−; 783.0000 [M−H−Xyl−Glc]−; 621.4186 [M−H−Xyl−2Glc]−; 459.3711 [M−H−Xyl−3Glc]−	23, 28
30	Malonyl-Rb3	27.8 90	C56H92 O25	1164.5 928	1163.5 896	3.5	1119.5832 [M−H−CO2]−; 1077.5738 [M−H−mal]−; 945.5557 [M−H−mal−Xyl]−; 783.4785 [M−H−mal−Xyl−Glc]−; 621.4281 [M−H−mal−Xyl−2Glc]−	23, 28
31	Notoginsenoside Fc	28.2 78	C58H98 O26	1210.6 346	1209.6 222	−3.8	1077.6158 [M−H−Xyl]−; 945.5410 [M−H−Xyl−Arap]−; 783.4793 [M−H−Xyl−Arap−Glc]−; 621.4312 [M−H−Xyl−Arap−2Glc]−; 459.3830 [M−H−Xyl−Arap−3Glc]−	24
32	Quinquenoside R1	28.7 63	C56H94 O24	1150.6 135	1149.6 118	−2.8	1107.5836 [M−H−AC]−; 1089.5745 [M−H−AC−H2O]−; 945.5285 [M−H−AC−Glc]−; 783.4795 [M−H−AC−2Glc]−; 621.4282 [M−H−AC−3Glc]−; 459.3848 [M−H−AC−4Glc]−	24
33	Chikusetsusaponi n IVa	29.2 61	C42H66 O14	794.44 53	793.44 06	3.9	631.3770 [M−H−Glc]−; 613.7845 [M−H−Glc−H2O]−; 569.3789 [M−H−2Glc−CO2−H2O]−; 455.3485 [M−H−2Glc−Acid]−	21, 29
34	Ginsenoside Rd	29.5 32	C48H82 O18	946.55 01	945.54 57	3.0	783.4816 [M−H−Glc]−; 621.4299 [M−H−2Glc]−; 459.3781 [M−H−3Glc]−	23, 28
35	Ginsenoside Rs1	29.8 93	C55H92 O23	1120.6 029	1119.5 993	3.3	1077.5668 [M−H−Ac]−; 945.5472 [M−H−Ac−Arap]−; 783.4679 [M−H−Ac−Arap−Glc]−; 621.4302 [M−H−Ac−Arap−2Glc]−; 459.3709 [M−H−Ac−Arap−3Glc]−	28
36	Malonyl-Rd	30.2 5	C51H84 O21	1032.5 505	1031.5 408	−1.8	987.5372 [M−H−CO2]−; 945.5301 [M−H−mal]−; 783.4829 [M−H−mal−Glc]−; 621.4292 [M−H−mal−2Glc]−; 459.3823 [M−H−mal−3Glc]−	23, 28
37	Ginsenoside Rs2	30.6 49	C55H92 O23	1120.6 029	1119.6 003	4.6	1077.5742 [M−H−Ac]−; 945.5422 [M−H−Ac−Araf]−; 915.5121 [M−H−Ac−Glc]−; 783.4852 [M−H−Ac−Araf−Glc]−; 621.4312 [M−H−Ac−Araf−2Glc]−; 459.3818 [M−H−Ac−Araf−3Glc]−	28
38	Gypenoside XVII	31.0 41	C48H82 O18	946.55 01	945.54 24	−0.4	783.4831 [M−H−Glc]−; 621.4288 [M−H−2Glc]−; 459.3804 [M−H−3Glc]−	26
39	ginsenoside Ra6	31.1 36	C58H96 O24	1176.6 075	1175.6 025	2.0	1107.5847 [M−H−Bu]−; 945.5311 [M−H-Bu−Glc]−; 783.4826 [M−H-Bu−2Glc]−; 621.4338 [M−H-Bu−3Glc]−; 459.3887 [M−H-Bu−4Glc]−	22
40	ginsenoside Ra7	31.7 48	C57H94 O23	1146.6 186	1145.6 150	3.7	1077.5731 [M−H−Bu]−; 945.5274 [M−H−Bu−Araf]−; 783.4809 [M−H−Bu−Araf−Glc]−; 621.4315 [M−H−Bu−Araf−2Glc]−; 459.3795 [M−H−Bu−Araf−3Glc]−	22
41	Compound Mc-1	31.8 68	C47H80 O17	916.53 90	915.52 99	−2.0	783.4833 [M−H−Araf]−; 621.4284 [M−H−Araf−Glc]−; 459.3816 [M−H−Araf−2Glc]−	26
42	Compound O	32.0 33	C47H80 O17	916.53 90	915.53 00	−1.9	783.4795 [M−H−Arap]−; 621.4306 [M−H−Arap−Glc]−; 459.3778 [M−H−Arap−2Glc]−	26
43	Pseudoginsenosid e Rc1	32.1 24	C50H84 O19	988.56 07	987.55 61	3.2	945.5316 [M−H−AC]−; 783.4837 [M−H−AC−Glc]−; 621.4302 [M−H−AC−2Glc]−; 459.3802 [M−H−AC−3Glc]−	26
44	ginsenoside Ra8/Ra9	32.3 05	C57H94 O23	1146.6 18	1145.6 155	4.2	1077.5731 [M−H−Bu]−; 945.5274 [M−H−Bu−Araf]−; 783.4809 [M−H−Bu−Araf−Glc]−; 621.4315 [M−H−Bu−Araf−2Glc]−; 459.3795 [M−H−Bu−Araf−3Glc]−	22
45	Gypenoside IX	32.4 46	C47H80 O17	916.53 90	915.53 52	3.8	961.5394 [M+HCOO]−; 783.4812 [M−H−Xyl]−; 621.4284 [M−H−Xy−Glc]−; 459.3864 [M−H−Xy−2Glc]−	26
46	Bu-Gypenoside XVII	33.7 09	C52H86 O19	1014.5 757	1013.5 650	−3.4	945.5287 [M−H−Bu]−; 783.4796 [M−H-Bu−Glc]−; 621.4307 [M−H-Bu−2Glc]−; 459.3760 [M−H-Bu−3Glc]−	22
47	20(S)-Ginsenosid e Rg3/isomer	34.0 69	C42H72 O13	784.49 73	783.48 86	−1.8	621.4291 [M−H−Glc]−; 459.3784 [M−H−2Glc]−	23, 28
48	Zingibroside R1	34.6 13	C42H66 O14	794.44 53	793.44 10	4.4	631.3742 [M−H−Glc]−; 613.3672 [M−H−Glc−H2O]−; 569.3779 [M−H−2Glc−CO2−H2O]−; 455.3474 [M−H−2Glc−Acid]−	26, 29
49	Bu-Rd	34.7 09	C52H86 O19	1014.5 763	1013.5 672	−1.3	945.5314 [M−H−Bu]−; 783.4778 [M−H-Bu−Glc]−; 621.4255 [M−H-Bu−2Glc]−; 459.3775[M−H-Bu−3Glc]−	22
50	20(R)-Ginsenosid e Rg3/isomer	35.5 36	C42H72 O13	784.49 73	783.49 27	3.4	621.4245 [M−H−Glc]−; 459.3759 [M−H−2Glc]−	23, 28
51	24(R)-pseudogins enoside RT5	38.6 59	C33H58 O14	678.38 27	677.37 60	1.6	677.3823 [M−H]−;	24
52	Ginsenoside Rk1	39.3 51	C42H70 O12	766.48 67	765.47 69	−2.6	03.4125 [M−H−Glc]−	23, 28
53	Ginsenoside Rg5	39.7 82	C42H70 O12	766.48 67	765.47 59	−3.9	603.4125 [M−H−Glc]−	23, 28
54	Ginsenoside Rh2	40.1 17	C36H62 O8	622.44 45	621.43 86	3.1	459.3792 [M−H−Glc]−	23, 28

^a[M−H]⁻;

Glc=β-D-glucopyranosyl (162 Da); Rha=α-L-rhamnopyranosyl (146 Da);

Ara=β-D-arabopyranosyl (132 Da); Xyl=β-D-Xylopyranosyl (132 Da);

Glc-Acid=β-D-glucopyranosylacetyl acid (176 Da); Ac=acetyl (42 Da); Bu=trans-but-2-enoyl (68 Da); Mal=malonyl (86 Da).