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. 2016 Nov 30;11(11):e0167069. doi: 10.1371/journal.pone.0167069

Table 4. Fold change in transcript abundance in DSLD-Paso and NA-Paso Cells treated with LY2109761.

Gene Fold Change in Transcript Abundance
(LY2109761: None)
DSLD Paso1 NA Paso1
PTK2B 2.11* 2.12*
ATF3 -1.27 1.16
MAPK14 3.12* 1.97
ME2 1.11 1.27
ACVRL1 2.42* -11.11*
NFIB -1.28 1.28
EPHB2 1.52 1.73
HMOX1 -1.27 1.85
SMAD6 1.39 1.12
FOS 1.34 3.85*
GLI2 -1.20 1.37
STC2 -1.96 1.41
ID2 1.01 1.31
PPARA 1.20 -1.03
ENG -1.54 -1.20
CREBBP 1.48 1.26
NFKBIA 1.51 1.29
BRD2 1.24 1.15
TGFBR2 2.36* 2.02
MMP2 1.56 1.34
CDKN1B 1.37 1.29
EP300 1.24 1.16
FURIN -1.96 1.59
MBD1 -1.06 1.28
IFRD1 -1.41 -1.03
SMAD3 1.35 1.25
BCL2L1 1.13 1.99
MAPK8 -1.47 1.19
SMAD1 1.25 1.15
RHOA -1.01 1.06
BACH1 -1.27 -1.45
MYC -1.12 1.38
PAI-1 -2.22* -1.52
ID3 1.09 1.16
SNAI1 -1.47 -1.25

1Mean abundance data for NA-Pasos (n = 2) and DSLD-Pasos (n = 2) was used (see S1 Table for animal details) to calculate fold change as described in Methods. Genes are listed in the same order as in Table 1.

(*) Significantly affected by LY2109761, p<0.05