Table 2. MICs based on the comparison of the MycoTB plate and MGIT 960 results.

MGIT 960			MYCOTB											7H10/ 7H11 CC, μg/ml	Raw agreement	Cohen’s Kappa
Critical concentration (CC)	Result	No. of strains	Determined MIC (μg/ml) and no. of isolates a									No. of resistant	No. of susceptible
Streptomycin			0.25	0.5	1	2	4	8	16	32	>32
1 μg/ml	R	117			2	3	13	14	5	7	73	112	5	2	0.97	0.89
	S	27	16	6	4	1						0	27
Rifampin			0.13	0.25	0.5	1	2	4	8	16	>16
1 μg/ml	R	107					2	1	3	2	99	107	0	1	1.00	1.00
	S	37	27	4	4	2						0	37
Isoniazid			0.03	0.06	0.13	0.25	0.5	1	2	4	>4
0.1 μg/ml	R	119			2	1	2	4	17	5	88	117	2	0.2	0.98	0.93
	S	25	14	10		1						1	24
Ethambutol			0.5	1	2	4	8	16	32	>32
5 μg/ml	R	79			1	11	52	13	2			67	12	5	0.90	0.79
	S	65	9	15	16	22	3					3	62
Ofloxacin			0.25	0.5	1	2	4	8	16	32
2 μg/ml	R	54				2	17	16	13	6		52	2	2	0.99	0.97
	S	90	25	39	23	3						0	90
Moxifloxacin			0.06	0.13	0.25	0.5	1	2	4	8
0.25 μg/ml	R	55			2	5	12	11	14	11		48	7	0.5	0.95	0.89
	S	89	29	18	37	5						0	89
Kanamycin			0.63	1.25	2.5	5	10	20	40	>40
2.5 μg/ml	R	73			5	20	19	6	23			48	25	5	0.83	0.65
	S	71	24	34	13							0	71
Amikacin			0.13	0.25	0.5	1	2	4	8	16	>16
1 μg/ml	R	35			1	2	4		6	22		28	7	4	0.95	0.86
	S	109	16	44	33	15	1					0	109
PAS			0.5	1	2	4	8	16	32	64	>64
4 μg/ml	R	31			3	3	8	9	3	3	2	28	3	2	0.94	0.83
	S	98	51	32	10	4		1				5	93
Ethionamide			0.31	0.63	1.25	2.5	5	10	20	40	>40
5 μg/ml	R	71				7	16	26	6	9	7	48	23	5	0.79	0.59
	S	58	1	5	14	10	24	3	1			4	54

^a Vertical bold line splits susceptible and resistant isolates based on the critical concentrations established for the agar proportion method.