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. 2016 Nov 30;11(11):e0167335. doi: 10.1371/journal.pone.0167335

Table 1. Antimicrobial susceptibility and biofilm formation ability of Haemophilus influenzae clinical isolates.

Strain Isolation site Serotypea Minimum inhibitory concentration (μg/mL)b Biofilm formation (OD630) c P valued
Ampicillin Ampicillin sulbactam Cefotaxime Clarithromycin Azithromycin Levofloxacin Without OdiE With OdiE (20 mg/mL)
2013–28 Nasal cavity Nontypeable 0.125 0.125 ≤0.063 2 0.25 ≤0.063 0.253 ± 0.061 0.096± 0.032 <0.001
2013–86 Nasal cavity Nontypeable 0.25 0.25 ≤0.063 4 0.5 ≤0.063 0.292 ± 0.047 0.098 ± 0.032 <0.001
2011–130 Nasal cavity Nontypeable 8 4 1 2 0.125 ≤0.063 0.193 ± 0.025 0.104 ± 0.039 <0.001

aSerotype was determined by PCR

bminimum inhibitory concentration was measured by the broth dilution method according to the Clinical and Laboratory Standards Institute guidelines

cmean ± SD

dP values were calculated by the Student's t-test.