Table IX.

— Summary of meta-analyses of prospective randomized studies to evaluate the proposed method of embryo selection.

Method of embryo selection	Outcome studied	Statistical difference found	Odds ratio (95% confidence intervals)	Reference
Scoring at the blastocyst stage	Live birth	Yes, if equal number of embryos are transferred	1.40 (95% CI = 1.13-1.74)	Glujovsky et al., 2012 (Cochrane review)
	Cumulative pregnancy rate	Yes, but in favor of day 2-3 transfers, compared to single blastocyst	1.58 (95% CI = 1.11-2.25)	Glujovsky et al., 2012 (Cochrane review)
Morpho-kinetics by time-lapse systems	Live birth	No	1.11 (95% CI = 0.45-2.73)	Armstrong et al., 2015 (Cochrane review)
	Clinical pregnancy	No	1.23 (95% CI = 0.96-1.59)	Armstrong et al., 2015 (Cochrane review)
Embryo metabolome in culture medium	Live birth	No	0.98 (95% CI = 0.74-1.29)	Vergouw et al., 2014 (Meta-analysis)