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Trabecular bone erosion with cyst formation in ACLX knee over time. Coronal in vivo micro-CT view at pre-surgical (a), 1 (b), 2 (c), 3 (d), 4 (e), and 5 (f) months post-surgery. Note the breach and eventual covering of the subchondral plate with immature bone (arrowheads), and the increasing area of cysts over time (arrows) within the same animal. These results are representative of findings in all ACLX animals in this study.
