Table I.

Descriptive statistics for compartmental vBMD (mean ± SD), body weight (mean ± SD) in grams, and OARSI score (mean ± SD) for the SHAM, LEFT, and ACLX rodents throughout the course of the experiment. Note the body weights for the ACLX and LEFT groups (both hind limbs of the same rat) are identical. The OARSI score represents the average score for both femoral and tibial joint surfaces

	vBMD (mg cm−3)						OARSI score
Compartment	Pre-surgical	1 month	2 months	3 months	4 months	5 months	5 months
SHAM	n = 3 (292 ± 9 g)	n = 3 (383 ± 8 g)	n = 3 (424 ± 13 g)	n = 3 (490 ± 3 g)	n = 3 (549 ± 7 g)	n = 3 (596 ± 6 g)	n = 3
LFC	502 ± 41	700 ± 52	722 ± 84	695 ± 22	719 ± 63	744 ± 46	0.3 ± 0.3
MFC	463 ± 56	657 ± 24	671 ± 77	659 ± 36	697 ± 86	720 ± 58
LTP	489 ± 50	641 ± 78	647 ± 91	638 ± 54	643 ± 100	694 ± 81
MTP	507 ± 64	704 ± 58	716 ± 90	700 ± 23	710 ± 55	740 ± 9
LEFT	n = 15 (310 ± 9 g)	n = 15 (409 ± 9 g)	n = 12 (463 ± 13 g)	n = 9 (519 ± 18 g)	n = 6 (579 ± 9 g)	n = 3 (622 ± 16 g)	n = 3
LFC	533 ± 57	696 ± 101	654 ± 66	685 ± 46	689 ± 74	796 ± 56	1.6 ± 1.3
MFC	543 ± 51	685 ± 88	672 ± 68	664 ± 28	674 ± 37	751 ± 77
LTP	530 ± 54	646 ± 90	649 ± 52	659 ± 44	626 ± 51	708 ± 55
MTP	574 ± 54	723 ± 93	721 ± 91	718 ± 48	731 ± 11	818 ± 82
ACLX	n = 15	n = 15	n = 12	n = 9	n = 6	n = 3	n = 3
LFC	528 ± 68	621 ± 52	705 ± 53	688 ± 50	647 ± 47	684 ± 49	19.8 ± 1.7
MFC	511 ± 74	584 ± 49	679 ± 35	650 ± 53	598 ± 42	669 ± 69
LTP	513 ± 66	556 ± 67	636 ± 51	618 ± 70	582 ± 59	638 ± 26
MTP	546 ± 69	624 ± 69	706 ± 54	660 ± 84	626 ± 68	683 ± 43