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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Curr Opin Hematol. 2016 Nov;23(6):524–529. doi: 10.1097/MOH.0000000000000282

Table 1.

Summary of MA, HLA-identical HSCT for SCD.

Ref. n, age range (years) Graft failure Acute GVHD, Grade II-IV Chronic GVHD Overall survival Disease-free survival
Walters et al[10] n=22 3-14 18% 9% 4.5% 91% at 4 years 73% at 4 years
Panepinto et al** [11] n=67 13.4% 10% 22% 97% at 5 years 85% at 5 years
Bernaudin et al [12] n=87 2-22 22.6%/ 3%* 20% 12.6% 93.1% at 6 years 86.1% at 6 years
Dedeken et al [13] n=50 1-15 8% 22% 20% 94.1% at 8 years 85.6% at 8 years
García-Morin et al[14] n=11 2-13 18% 55% 0% 90.9% at 3 years 81.9% at 3 years
Dallas et al (MRD cohort) [15] n=14 5-17 0% 28% 21% 93% at 9 years 93% at 9 years
*

Graft failure was 22% in patients who did not receive ATG during conditioning, and 3% in patients who received ATG during conditioning.

**

Study included an unknown number of patients reported in Walters et al (1996).