Table 1.
Ref. | n, age range (years) | Graft failure | Acute GVHD, Grade II-IV | Chronic GVHD | Overall survival | Disease-free survival |
---|---|---|---|---|---|---|
Walters et al[10] | n=22 3-14 | 18% | 9% | 4.5% | 91% at 4 years | 73% at 4 years |
Panepinto et al** [11] | n=67 | 13.4% | 10% | 22% | 97% at 5 years | 85% at 5 years |
Bernaudin et al [12] | n=87 2-22 | 22.6%/ 3%* | 20% | 12.6% | 93.1% at 6 years | 86.1% at 6 years |
Dedeken et al [13] | n=50 1-15 | 8% | 22% | 20% | 94.1% at 8 years | 85.6% at 8 years |
García-Morin et al[14] | n=11 2-13 | 18% | 55% | 0% | 90.9% at 3 years | 81.9% at 3 years |
Dallas et al (MRD cohort) [15] | n=14 5-17 | 0% | 28% | 21% | 93% at 9 years | 93% at 9 years |
Graft failure was 22% in patients who did not receive ATG during conditioning, and 3% in patients who received ATG during conditioning.
Study included an unknown number of patients reported in Walters et al (1996).