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Effect of combinations of enalapril and PAI-1 antibody on protein production of total collagen (A) and FN (B) in renal cortex tissue in diabetic db/db mice. PAI-1 Ab, diabetic db/db mice treated with MEDI-579. *P < 0.05 vs. db/m. #P < 0.05 vs. db/db-22wk. §P < 0.05 vs. enalapril plus control IgG-treated diabetic db/db mice (db/db+Ena+Con Ab).
