Table 1.

Experimental groups

Group	N	Genotype	Water	Injection
db/m	8	db/m	Regular water	PBS ip, twice a week, starting from week 18
db/db	9	db/db	Regular water	PBS ip, twice a week, starting from week 18
db/db+PAI-1 Ab	8	db/db	Regular water	3 mg/kg BW, PAI-1 antibody ip, twice a week, starting from week 18
db/db+Ena+Con Ab	9	db/db	200 mg/l enalapril, starting from week 12	3 mg/kg BW, isotope antibody ip, twice a week, starting from week 18
db/db+Ena+PAI-1 Ab	9	db/db	200 mg/l enalapril, starting from week 12	3 mg/kg BW, PAI-1 antibody ip, twice a week, starting from week 18

PAI-1, plasminogen activator inhibitor type 1; ip, intraperitoneally; BW, body wt. See the text for additional definitions.