Mean seizure spike amplitude distribution among head-cooled and control groups 1–30 min after seizure onset (N = 6 in each group). The number of spikes in the 0.25–2.00 amplitude ranges were analyzed for 1- to 5-min (A), 5- to 10-min (B), 10- to 15-min (C), 15- to 20-min (D), 20- to 25-min (E), and 25- to 30-min (F) segments after seizure onset. Values are means ± SE. *P < 0.05 compared with the normothermic values.